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C6EBF0 (C6EBF0_ECOBD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase HAMAP MF_01437
EC=2.7.8.5 HAMAP MF_01437
Alternative name(s):
Phosphatidylglycerophosphate synthase HAMAP MF_01437
Gene names
Name:pgsA HAMAP MF_01437 EMBL ACT43731.1
Ordered Locus Names:B21_01866, ECBD_1731, ECD_01877
OrganismEscherichia coli (strain B / BL21-DE3) [Complete proteome] [HAMAP]
Taxonomic identifier469008 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length182 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein catalyzes the committed step to the synthesis of the acidic phospholipids By similarity. HAMAP MF_01437

Catalytic activity

CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate. HAMAP MF_01437

Pathway

Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2. HAMAP MF_01437

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP MF_01437.

Sequence similarities

Belongs to the CDP-alcohol phosphatidyltransferase class-I family. RuleBase RU003750 HAMAP MF_01437

Sequences

Sequence LengthMass (Da)Tools
C6EBF0 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: F8F0502ABE6DC8D5

FASTA18220,701
        10         20         30         40         50         60 
MQFNIPTLLT LFRVILIPFF VLVFYLPVTW SPFAAALIFC VAAVTDWFDG FLARRWNQST 

        70         80         90        100        110        120 
RFGAFLDPVA DKVLVAIAMV LVTEHYHSWW VTLPAATMIA REIIISALRE WMAELGKRSS 

       130        140        150        160        170        180 
VAVSWIGKVK TTAQMVALAW LLWRPNIWVE YAGIALFFVA AVLTLWSMLQ YLSAARADLL 


DQ

« Hide

References

[1]"Genome sequences of Escherichia coli B strains REL606 and BL21(DE3)."
Jeong H., Barbe V., Lee C.H., Vallenet D., Yu D.S., Choi S.H., Couloux A., Lee S.W., Yoon S.H., Cattolico L., Hur C.G., Park H.S., Segurens B., Kim S.C., Oh T.K., Lenski R.E., Studier F.W., Daegelen P., Kim J.F.
J. Mol. Biol. 394:644-652(2009) [PubMed: 19786035] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B / BL21-DE3 [Korea].
[2]"Sequencing and gene expression analysis of Escherichia coli BL21."
Leparc G., Striedner G., Bayer K., Kreil D., Krempl P.M.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B / BL21-DE3 [Austria].
[3]"Complete sequence of Escherichia coli BL21(DE3)."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B / BL21-DE3 [JGI].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001665 Genomic DNA. Translation: ACT28782.1.
CP001509 Genomic DNA. Translation: ACT43731.1.
AM946981 Genomic DNA. Translation: CAQ32383.1.

3D structure databases

ProteinModelPortalC6EBF0.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6EBF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000157468; EBESCP00000147132; EBESCG00000158919.
EBESCT00000189636; EBESCP00000178381; EBESCG00000190369.
EBESCT00000194261; EBESCP00000182710; EBESCG00000193540.
GenomeReviewsGene locus B21_01866 in contig AM946981_GR.
Gene locus ECD_01877 in contig CP001509_GR.
Gene locus ECBD_1731 in contig CP001665_GR.
KEGGebd:ECBD_1731.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000009502.
OMAWSYMAAS.
ProtClustDBPRK10832.

Family and domain databases

HAMAPMF_01437. PgsA.
[Tree]
InterProIPR000462. CDP-OH_P_trans.
IPR023762. PGP_synthase_bac.
IPR004570. Phosphatidylglycerol_P_synth.
[Graphical view]
KOK00995.
PfamPF01066. CDP-OH_P_transf. 1 hit.
[Graphical view]
PIRSFPIRSF000847. Phos_ph_gly_syn. 1 hit.
TIGRFAMsTIGR00560. PgsA. 1 hit.
PROSITEPS00379. CDP_ALCOHOL_P_TRANSF. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6EBF0_ECOBD
AccessionPrimary (citable) accession number: C6EBF0
Secondary accession number(s): C5W5F0
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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