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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Geobacter sp. (strain M21)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi8 – 81Divalent metal cationUniRule annotation
Metal bindingi9 – 91Divalent metal cationUniRule annotation
Metal bindingi39 – 391Divalent metal cationUniRule annotation
Metal bindingi91 – 911Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGSP443144:GHKM-1586-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:GM21_1555
OrganismiGeobacter sp. (strain M21)
Taxonomic identifieri443144 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000002380 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2482485'-nucleotidase SurEPRO_1000202369Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi443144.GM21_1555.

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiEOG68WR45.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

C6E582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILLTNDDG VHSPGLAALI KKVSEVAEVV VVAPDREQSA VSHALTLHHP
60 70 80 90 100
LRAARIRANV FSVEGTPTDC VNLGIHSLLS YRPDLVISGV NRGANIADDV
110 120 130 140 150
TYSGTVAAAL EATLMGIPAI AVSLVTRSAG EHFEAAAACA AKLAVTVHQK
160 170 180 190 200
GLPRDTYLNV NVPDLPAESL LPPLITCQGK RSYEGTIVDK VDPRGRNYYW
210 220 230 240
IGTTDLSFED IPGTDYHAVS RGHVSISPLH IDLTNHASIE TLKSWELP
Length:248
Mass (Da):26,492
Last modified:September 1, 2009 - v1
Checksum:i3292AC7ECDE67A6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA. Translation: ACT17611.1.
RefSeqiWP_015836860.1. NC_012918.1.

Genome annotation databases

EnsemblBacteriaiACT17611; ACT17611; GM21_1555.
KEGGigem:GM21_1555.
PATRICi22017560. VBIGeoSp56140_1513.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA. Translation: ACT17611.1.
RefSeqiWP_015836860.1. NC_012918.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi443144.GM21_1555.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT17611; ACT17611; GM21_1555.
KEGGigem:GM21_1555.
PATRICi22017560. VBIGeoSp56140_1513.

Phylogenomic databases

eggNOGiENOG4105CV2. Bacteria.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiNLNIPPC.
OrthoDBiEOG68WR45.

Enzyme and pathway databases

BioCyciGSP443144:GHKM-1586-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M21.

Entry informationi

Entry nameiSURE_GEOSM
AccessioniPrimary (citable) accession number: C6E582
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: November 11, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.