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Protein

Superoxide dismutase [Cu-Zn]

Gene

GM21_3067

Organism
Geobacter sp. (strain M21)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciGSP443144:GHKM-3114-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:GM21_3067Imported
OrganismiGeobacter sp. (strain M21)Imported
Taxonomic identifieri443144 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000002380: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323 PotentialImportedAdd
BLAST
Chaini24 – 175152 PotentialImportedPRO_5000486887Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi443144.GM21_3067.

Structurei

3D structure databases

ProteinModelPortaliC6E3A3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiGLHFHEK.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C6E3A3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKGNTCATF IALCLFTGTA HAMSHVKARA EIRDASGKTV GTATFTEQKE
60 70 80 90 100
GVKVEIAVSG LPPGQHGFHI HENGTCLPPD FKSAGGHFNP FKKHHGSDNP
110 120 130 140 150
AGKHAGDFPN LEVKDDGTAK TTVVAAGATL RKGPGSLLKP GGTAIVIHAN
160 170
PDDYQSDPAG NAGDRVACGV IVKAK
Length:175
Mass (Da):18,030
Last modified:September 1, 2009 - v1
Checksum:i178D7D45911333C8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA. Translation: ACT19095.1.
RefSeqiWP_015838312.1. NC_012918.1.
YP_003022853.1. NC_012918.1.

Genome annotation databases

EnsemblBacteriaiACT19095; ACT19095; GM21_3067.
GeneIDi8138413.
KEGGigem:GM21_3067.
PATRICi22020514. VBIGeoSp56140_2975.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001661 Genomic DNA. Translation: ACT19095.1.
RefSeqiWP_015838312.1. NC_012918.1.
YP_003022853.1. NC_012918.1.

3D structure databases

ProteinModelPortaliC6E3A3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi443144.GM21_3067.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT19095; ACT19095; GM21_3067.
GeneIDi8138413.
KEGGigem:GM21_3067.
PATRICi22020514. VBIGeoSp56140_2975.

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiGLHFHEK.
OrthoDBiEOG6K13RS.

Enzyme and pathway databases

BioCyciGSP443144:GHKM-3114-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: M21Imported.

Entry informationi

Entry nameiC6E3A3_GEOSM
AccessioniPrimary (citable) accession number: C6E3A3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: January 7, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.