C6DSB5 (C6DSB5_MYCTK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-glucose 6-dehydrogenase udgA EMBL ACT23354.1

Gene names

Ordered Locus Names:

TBMG_00326

Organism

Mycobacterium tuberculosis (strain KZN 1435 / MDR) [Complete proteome] [HAMAP]

Taxonomic identifier

478434 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium tuberculosis

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. PIRNR PIRNR000124

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6DSB5 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: BBCC0FC59AFC41EA	FASTA	443	47,362
	10 20 30 40 50 60 MRCSVFGTGY LGATHAVGMA QLGHEVVGVD IDPGKVAKLA GGDIPFYEPG LRKLLTDNLA 70 80 90 100 110 120 AGRLRFTTDY DMAADFADVH FLGVGTPQKI GEYGADLRHV HAVIDALVPR LVRASILVGK 130 140 150 160 170 180 STVPVGTAAE LGHRAGALAP RGVDVEIAWN PEFLREGFAV HDTLNPDRIV LGVQDDSTRA 190 200 210 220 230 240 EVAVRELYAP LLAAGVPFLV TDLQTAELVK VSANAFLATK ISFINAISEV CEAAGADVSQ 250 260 270 280 290 300 LADALGYDPR IGRQCLNAGL GFGGGCLPKD IRAFMARAGE LGADQALTFL REVDSINMRR 310 320 330 340 350 360 RTKMVELATT ACGGSLLGAN IAVLGAAFKP ESDDVRDSPA LNVAGQLQLN GATVHVYDPK 370 380 390 400 410 420 ALDNAHRLFP TLNYAVSVAE ACERADAVLV LTEWREFIDL EPADLANRVR ARVIVDGRNC 430 440 LDVTRWRRAG WRVFRLGVPR LGH

References

[1]

"The genome sequence of Mycobacterium tuberculosis strain KZN 1435." Murray M., Pillay M., Borowsky M.L., Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I., Hepburn T.A. , Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C., Haas B., Nusbaum C., Galagan J., Birren B. Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KZN 1435 / MDR.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001658 Genomic DNA. Translation: ACT23354.1.
RefSeq	YP_003030249.1. NC_012943.1.
3D structure databases
ProteinModelPortal	C6DSB5.
SMR	C6DSB5. Positions 1-439.
ModBase	Search...
Protein-protein interaction databases
STRING	478434.TBMG_00326.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT23354; ACT23354; TBMG_00326.
GeneID	8162500.
KEGG	mtb:TBMG_00326.
PATRIC	18158058. VBIMycTub122270_0355.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1004.
HOGENOM	HOG000153773.
KO	K00012.
OMA	QMCPEIR.
ProtClustDB	CLSK871786.
Enzyme and pathway databases
BioCyc	MTUB478434:GH8E-337-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR016040. NAD(P)-bd_dom. IPR017476. Nucleotide_sugar_DH. IPR014027. UDP-Glc/GDP-Man_DH_C. IPR014026. UDP-Glc/GDP-Man_DH_dimer. IPR001732. UDP-Glc/GDP-Man_DH_N. [Graphical view]
Pfam	PF00984. UDPG_MGDP_dh. 1 hit. PF03720. UDPG_MGDP_dh_C. 1 hit. PF03721. UDPG_MGDP_dh_N. 1 hit. [Graphical view]
PIRSF	PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMART	SM00984. UDPG_MGDP_dh_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit. SSF52413. UDP-Glc/GDP-Man_DH_C. 1 hit.
TIGRFAMs	TIGR03026. NDP-sugDHase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6DSB5_MYCTK

Accession

Primary (citable) accession number: C6DSB5

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)