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C6DRM8

- C6DRM8_MYCTK

UniProt

C6DRM8 - C6DRM8_MYCTK

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Protein
Submitted name: Aldehyde dehydrogenase
Gene
TBMG_00224, V460_03792
Organism
Mycobacterium tuberculosis (strain KZN 1435 / MDR)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Enzyme and pathway databases

    BioCyciMTUB478434:GH8E-233-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Aldehyde dehydrogenaseImported
    Submitted name:
    Aldehyde dehydrogenase (NAD+)Imported
    Gene namesi
    Ordered Locus Names:TBMG_00224Imported
    ORF Names:V460_03792Imported
    OrganismiMycobacterium tuberculosis (strain KZN 1435 / MDR)
    Taxonomic identifieri478434 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000002737: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi478434.TBMG_00224.

    Structurei

    3D structure databases

    ProteinModelPortaliC6DRM8.
    SMRiC6DRM8. Positions 4-486.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiYMAGWAR.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6DRM8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDSATEYDK LFIGGKWTKP STSDVIEVRC PATGEYVGKV PMAAAADVDA    50
    AVAAARAAFD NGPWPSTPPH ERAAVIAAAV KMLAERKDLF TKLLAAETGQ 100
    PPTIIETMHW MGSMGAMNYF AGAADKVTWT ETRTGSYGQS IVSREPVGVV 150
    GAIVAWNVPL FLAVNKIAPA LLAGCTIVLK PAAETPLTAN ALAEVFAEVG 200
    LPEGVLSVVP GGIETGQALT SNPDIDMFTF TGSSAVGREV GRRAAEMLKP 250
    CTLELGGKSA AIILEDVDLA AAIPMMVFSG VMNAGQGCVN QTRILAPRSR 300
    YDEIVAAVTN FVTALPVGPP SDPAAQIGPL ISEKQRTRVE GYIAKGIEEG 350
    ARLVCGGGRP EGLDNGFFIQ PTVFADVDNK MTIAQEEIFG PVLAIIPYDT 400
    EEDAIAIAND SVYGLAGSVW TTDVPKGIKI SQQIRTGTYG INWYAFDPGS 450
    PFGGYKNSGI GRENGPEGVE HFTQQKSVLL PMGYTVA 487
    Length:487
    Mass (Da):51,157
    Last modified:September 1, 2009 - v1
    Checksum:i456B13AD0D5672EE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001658 Genomic DNA. Translation: ACT23251.1.
    JLCO01000005 Genomic DNA. Translation: KBN04012.1.
    RefSeqiYP_003030146.1. NC_012943.1.

    Genome annotation databases

    EnsemblBacteriaiACT23251; ACT23251; TBMG_00224.
    GeneIDi8161873.
    KEGGimtb:TBMG_00224.
    PATRICi18157844. VBIMycTub122270_0248.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001658 Genomic DNA. Translation: ACT23251.1 .
    JLCO01000005 Genomic DNA. Translation: KBN04012.1 .
    RefSeqi YP_003030146.1. NC_012943.1.

    3D structure databases

    ProteinModelPortali C6DRM8.
    SMRi C6DRM8. Positions 4-486.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 478434.TBMG_00224.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT23251 ; ACT23251 ; TBMG_00224 .
    GeneIDi 8161873.
    KEGGi mtb:TBMG_00224.
    PATRICi 18157844. VBIMycTub122270_0248.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi YMAGWAR.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci MTUB478434:GH8E-233-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KZN 1435 / MDR.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: KZN 1435Imported.

    Entry informationi

    Entry nameiC6DRM8_MYCTK
    AccessioniPrimary (citable) accession number: C6DRM8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: July 9, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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