C6DMA5 (C6DMA5_MYCTK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-aminobutyrate aminotransferase gabT EMBL ACT24436.1

Gene names

Ordered Locus Names:

TBMG_01383

Organism

Mycobacterium tuberculosis (strain KZN 1435 / MDR) [Complete proteome] [HAMAP]

Taxonomic identifier

478434 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex › Mycobacterium tuberculosis

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003560

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003560
Molecular function	Aminotransferase EMBL ACT24436.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6DMA5 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 9EB88A968B3D8719	FASTA	449	46,813
	10 20 30 40 50 60 MASLQQSRRL VTEIPGPASQ ALTHRRAAAV SSGVGVTLPV FVARAGGGIV EDVDGNRLID 70 80 90 100 110 120 LGSGIAVTTI GNSSPRVVDA VRTQVAEFTH TCFMVTPYEG YVAVAEQLNR ITPGSGPKRS 130 140 150 160 170 180 VLFNSGAEAV ENAVKIARSY TGKPAVVAFD HAYHGRTNLT MALTAKSMPY KSGFGPFAPE 190 200 210 220 230 240 IYRAPLSYPY RDGLLDKQLA TNGELAAARA IGVIDKQVGA NNLAALVIEP IQGEGGFIVP 250 260 270 280 290 300 AEGFLPALLD WCRKNHVVFI ADEVQTGFAR TGAMFACEHE GPDGLEPDLI CTAKGIADGL 310 320 330 340 350 360 PLSAVTGRAE IMNAPHVGGL GGTFGGNPVA CAAALATIAT IESDGLIERA RQIERLVTDR 370 380 390 400 410 420 LTTLQAVDDR IGDVRGRGAM IAVELVKSGT TEPDAGLTER LATAAHAAGV IILTCGMFGN 430 440 IIRLLPPLTI GDELLSEGLD IVCAILADL

References

[1]

"The genome sequence of Mycobacterium tuberculosis strain KZN 1435." Murray M., Pillay M., Borowsky M.L., Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I., Hepburn T.A. , Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C., Haas B., Nusbaum C., Galagan J., Birren B. Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KZN 1435 / MDR.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001658 Genomic DNA. Translation: ACT24436.1.
RefSeq	YP_003031330.1. NC_012943.1.
3D structure databases
ProteinModelPortal	C6DMA5.
SMR	C6DMA5. Positions 2-448.
ModBase	Search...
Protein-protein interaction databases
STRING	478434.TBMG_01383.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT24436; ACT24436; TBMG_01383.
GeneID	8163567.
KEGG	mtb:TBMG_01383.
PATRIC	18160442. VBIMycTub122270_1529.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0160.
HOGENOM	HOG000020206.
KO	K07250.
OMA	PGTHEKR.
ProtClustDB	PRK06058.
Enzyme and pathway databases
BioCyc	MTUB478434:GH8E-1435-MONOMER.
Family and domain databases
Gene3D	3.40.640.10. 1 hit. 3.90.1150.10. 1 hit.
InterPro	IPR004632. 4NH2But_aminotransferase_bac. IPR005814. Aminotrans_3. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
PANTHER	PTHR11986. PTHR11986. 1 hit.
Pfam	PF00202. Aminotran_3. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR00700. GABAtrnsam. 1 hit.
PROSITE	PS00600. AA_TRANSFER_CLASS_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C6DMA5_MYCTK

Accession

Primary (citable) accession number: C6DMA5

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)