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C6DLV3

- C6DLV3_MYCTK

UniProt

C6DLV3 - C6DLV3_MYCTK

Protein

Glutamate decarboxylase

Gene

TBMG_03480

Organism
Mycobacterium tuberculosis (strain KZN 1435 / MDR)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMTUB478434:GH8E-3603-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:TBMG_03480Imported
    ORF Names:V460_00461Imported
    OrganismiMycobacterium tuberculosis (strain KZN 1435 / MDR)Imported
    Taxonomic identifieri478434 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000002737: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiC6DLV3.

    Interactioni

    Protein-protein interaction databases

    STRINGi478434.TBMG_03480.

    Structurei

    3D structure databases

    ProteinModelPortaliC6DLV3.
    SMRiC6DLV3. Positions 12-447.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiPTFQINF.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6DLV3-1 [UniParc]FASTAAdd to Basket

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    MSRSHPSVPA HSIAPAYTGR MFTAPVPALR MPDESMDPEA AYRFIHDELM    50
    LDGSSRLNLA TFVTTWMDPE AEKLMAETFD KNMIDKDEYP ATAAIEARCV 100
    SMVADLFHAE GLRDHDPTSA TGVSTIGSSE AVMLGGLALK WRWRQRVGSW 150
    KGRMPNLVMG SNVQVVWEKF CRYFDVEPRY LPMERGRYVI TPEQVLAAVD 200
    ENTIGVVAIL GTTYTGELEP IAEICAALDK LAAGGGVDVP VHVDAASGGF 250
    VVPFLHPDLV WDFRLPRVVS INVSGHKYGL TYPGVGFVVW RGPEHLPEDL 300
    VFRVNYLGGD MPTFTLNFSR PGNQVVGQYY NFLRLGRDGY TKVMQALSHT 350
    ARWLGDQLRE VDHCEVISDG SAIPVVSFRL AGDRGYTEFD VSHELRTFGW 400
    QVPAYTMPDN ATDVAVLRIV VREGLSADLA RALHDDAVTA LAALDKVKPG 450
    GHFDAQHFAH 460
    Length:460
    Mass (Da):50,780
    Last modified:September 1, 2009 - v1
    Checksum:iB5DA3156D4C7CB4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001658 Genomic DNA. Translation: ACT26583.1.
    JLCO01000001 Genomic DNA. Translation: KBN06518.1.
    RefSeqiYP_003033478.1. NC_012943.1.

    Genome annotation databases

    EnsemblBacteriaiACT26583; ACT26583; TBMG_03480.
    GeneIDi8164382.
    KEGGimtb:TBMG_03480.
    PATRICi18165141. VBIMycTub122270_3856.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001658 Genomic DNA. Translation: ACT26583.1 .
    JLCO01000001 Genomic DNA. Translation: KBN06518.1 .
    RefSeqi YP_003033478.1. NC_012943.1.

    3D structure databases

    ProteinModelPortali C6DLV3.
    SMRi C6DLV3. Positions 12-447.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 478434.TBMG_03480.

    Proteomic databases

    PRIDEi C6DLV3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT26583 ; ACT26583 ; TBMG_03480 .
    GeneIDi 8164382.
    KEGGi mtb:TBMG_03480.
    PATRICi 18165141. VBIMycTub122270_3856.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi PTFQINF.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci MTUB478434:GH8E-3603-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KZN 1435 / MDRImported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: KZN 1435Imported.

    Entry informationi

    Entry nameiC6DLV3_MYCTK
    AccessioniPrimary (citable) accession number: C6DLV3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3