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C6DKY4 (BETA_PECCP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Choline dehydrogenase
Short name=CDH
Short name=CHD
EC=1.1.99.1
Gene names
Name:betA
Ordered Locus Names:PC1_2554
OrganismPectobacterium carotovorum subsp. carotovorum (strain PC1) [Complete proteome] [HAMAP]
Taxonomic identifier561230 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. HAMAP MF_00750

Catalytic activity

Choline + acceptor = betaine aldehyde + reduced acceptor. HAMAP MF_00750

Cofactor

FAD By similarity. HAMAP MF_00750

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. HAMAP MF_00750

Sequence similarities

Belongs to the GMC oxidoreductase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559Choline dehydrogenase HAMAP MF_00750
PRO_1000212847

Regions

Nucleotide binding4 – 3330FAD Potential

Sites

Active site4711 By similarity

Sequences

Sequence LengthMass (Da)Tools
C6DKY4 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: ED4A30801053D8E2

FASTA55962,162
        10         20         30         40         50         60 
MEYDYIIIGA GSAGNVLATR LTEESDVSVL LLEAGGPDYR LDFRTQMPAA LAFPLQGKRY 

        70         80         90        100        110        120 
NWAYETDPEP HMNNRRMECG RGKGLGGSSL INGMCYIRGN AMDFDNWATM PGLEDWSYLD 

       130        140        150        160        170        180 
CLPYFRKAET RDVGSNDYHG ATGPVSVATP KMGNNELFHA MVEAGVQAGY PRTDDLNGYQ 

       190        200        210        220        230        240 
QEGFGPMDRT VTPKGRRAST ARGYLDQAKG RKNLTIVTHA LTDKILFEGK RAVGVAYFKG 

       250        260        270        280        290        300 
ESPQTVQARR EVLLCAGAIA SPQILQRSGV GPKDLLQGLD IPVVHDLPGV GENLQDHLEM 

       310        320        330        340        350        360 
YLQYACKEPV SLYPALQWFN QPKIGAEWLF SGTGIGASNQ FEAGGFIRSR DEFAWPNIQY 

       370        380        390        400        410        420 
HFLPVAINYN GSNAVKEHGF QAHVGSMRSL SRGRVQVRSK DAREHPSILF NYMSTEQDWQ 

       430        440        450        460        470        480 
EFRDAIRITR EIMAQPALDK YRGREISPGL EVQTDEELDE FIRTHAETAF HPSCSCKMGE 

       490        500        510        520        530        540 
DEMAVVDGQG RVHGMEGLRV VDASIMPQII TGNLNATTIM IAEKIADRIR RRQPLPRSRA 

       550 
RYYVSGNTPV RKAPLKPAS

« Hide

References

[1]"Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Balakrishnan V., Glasner J., Perna N.T.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001657 Genomic DNA. Translation: ACT13585.1.
RefSeqYP_003018121.1. NC_012917.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC6DKY4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8133501.
GenomeReviewsGene locus PC1_2554 in contig CP001657_GR.
KEGGpct:PC1_2554.
PATRIC20489782. VBIPecCar70489_2574.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEISPGAH.
ProtClustDBPRK02106.

Family and domain databases

HAMAPMF_00750. Choline_dehydrogen.
[Tree]
InterProIPR011533. Choline_dehydrogenase.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
KOK00108.
PfamPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFPIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMsTIGR01810. BetA. 1 hit.
PROSITEPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETA_PECCP
AccessionPrimary (citable) accession number: C6DKY4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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