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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 29NADUniRule annotationAdd BLAST12

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:PC1_0530
OrganismiPectobacterium carotovorum subsp. carotovorum (strain PC1)
Taxonomic identifieri561230 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000002736 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002125061 – 488Altronate oxidoreductaseAdd BLAST488

Interactioni

Protein-protein interaction databases

STRINGi561230.PC1_0530.

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QZW. Bacteria.
COG0246. LUCA.
HOGENOMiHOG000029586.
KOiK00041.
OMAiVVIVRPI.
OrthoDBiPOG091H0H06.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct. 1 hit.
InterProiIPR013328. 6PGD_dom_2.
IPR023668. Altronate_OxRdtase.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6DKE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTLNRRNFP GRQHPDRVIQ FGEGNFLRAF VDWQLDLLNE HTDLDAGIVI
60 70 80 90 100
VRPIDSDFPP ALDTQDGLYT TIIRGLNEQG EAVREPRLIR SVNREINVYR
110 120 130 140 150
QFDEYLALAH DPNIRFVFSN TTEAGISYHA DDSLSDAPPV SFPAKLTRLL
160 170 180 190 200
YERFCHFDGA ADKGWVLLPC ELIDYNGVAL KELVLRYAAQ WKLTPTFTAW
210 220 230 240 250
LNDHNTFCST LVDRIVTGYP RAEVEALQQE MGYQDTFWDT AEHFYLFVIQ
260 270 280 290 300
GPQWLAEELR LNKLDLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG
310 320 330 340 350
LDTVGESMDD ALIGKFVEKT IAEEIVPVLD LPHDELTSFA QAVLSRFRNP
360 370 380 390 400
FIQHQLLSIS LNGMTKFRTR ILPQLLTYRE RHGELPARLT FALAALIAFY
410 420 430 440 450
RGERSGEGDT LQTYPLQDDA HWLERYSTLW AGVKENTVSL AELVNVVLRD
460 470 480
ADHWEQDLTQ VPGLAAQVTE QLQTIVERGM RAAVEGYC
Length:488
Mass (Da):55,573
Last modified:September 1, 2009 - v1
Checksum:i678B2D8CF35009A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001657 Genomic DNA. Translation: ACT11585.1.
RefSeqiWP_012773237.1. NC_012917.1.

Genome annotation databases

EnsemblBacteriaiACT11585; ACT11585; PC1_0530.
KEGGipct:PC1_0530.
PATRICi20485624. VBIPecCar70489_0524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001657 Genomic DNA. Translation: ACT11585.1.
RefSeqiWP_012773237.1. NC_012917.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi561230.PC1_0530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT11585; ACT11585; PC1_0530.
KEGGipct:PC1_0530.
PATRICi20485624. VBIPecCar70489_0524.

Phylogenomic databases

eggNOGiENOG4107QZW. Bacteria.
COG0246. LUCA.
HOGENOMiHOG000029586.
KOiK00041.
OMAiVVIVRPI.
OrthoDBiPOG091H0H06.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct. 1 hit.
InterProiIPR013328. 6PGD_dom_2.
IPR023668. Altronate_OxRdtase.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUXAB_PECCP
AccessioniPrimary (citable) accession number: C6DKE8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: November 30, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.