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C6DKE8 (UXAB_PECCP) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Altronate oxidoreductase

EC=1.1.1.58
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene names
Name:uxaB
Ordered Locus Names:PC1_0530
OrganismPectobacterium carotovorum subsp. carotovorum (strain PC1) [Complete proteome] [HAMAP]
Taxonomic identifier561230 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP-Rule MF_00670

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00670

Sequence similarities

Belongs to the mannitol dehydrogenase family. UxaB subfamily.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

tagaturonate reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 488488Altronate oxidoreductase HAMAP-Rule MF_00670
PRO_1000212506

Regions

Nucleotide binding18 – 2912NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
C6DKE8 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 678B2D8CF35009A3

FASTA48855,573
        10         20         30         40         50         60 
MQTLNRRNFP GRQHPDRVIQ FGEGNFLRAF VDWQLDLLNE HTDLDAGIVI VRPIDSDFPP 

        70         80         90        100        110        120 
ALDTQDGLYT TIIRGLNEQG EAVREPRLIR SVNREINVYR QFDEYLALAH DPNIRFVFSN 

       130        140        150        160        170        180 
TTEAGISYHA DDSLSDAPPV SFPAKLTRLL YERFCHFDGA ADKGWVLLPC ELIDYNGVAL 

       190        200        210        220        230        240 
KELVLRYAAQ WKLTPTFTAW LNDHNTFCST LVDRIVTGYP RAEVEALQQE MGYQDTFWDT 

       250        260        270        280        290        300 
AEHFYLFVIQ GPQWLAEELR LNKLDLNVRI VDDIKPYKER KVAILNGAHT ALVPVAFLAG 

       310        320        330        340        350        360 
LDTVGESMDD ALIGKFVEKT IAEEIVPVLD LPHDELTSFA QAVLSRFRNP FIQHQLLSIS 

       370        380        390        400        410        420 
LNGMTKFRTR ILPQLLTYRE RHGELPARLT FALAALIAFY RGERSGEGDT LQTYPLQDDA 

       430        440        450        460        470        480 
HWLERYSTLW AGVKENTVSL AELVNVVLRD ADHWEQDLTQ VPGLAAQVTE QLQTIVERGM 


RAAVEGYC 

« Hide

References

[1]"Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Balakrishnan V., Glasner J., Perna N.T.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PC1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001657 Genomic DNA. Translation: ACT11585.1.
RefSeqYP_003016121.1. NC_012917.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING561230.PC1_0530.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACT11585; ACT11585; PC1_0530.
GeneID8131447.
KEGGpct:PC1_0530.
PATRIC20485624. VBIPecCar70489_0524.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0246.
HOGENOMHOG000029586.
KOK00041.
OMARVIQFGE.
OrthoDBEOG6CVVB8.
ProtClustDBPRK03643.

Enzyme and pathway databases

BioCycPCAR561230:GKCK-547-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPMF_00670. Altron_oxidoreduct.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMSSF48179. SSF48179. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXAB_PECCP
AccessionPrimary (citable) accession number: C6DKE8
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: February 19, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways