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Protein

HTH-type transcriptional activator RhaR

Gene

rhaR

Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activates expression of the rhaSR operon in response to L-rhamnose.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi197 – 216H-T-H motifUniRule annotationAdd BLAST20
DNA bindingi246 – 269H-T-H motifUniRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Rhamnose metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaRUniRule annotation
Alternative name(s):
L-rhamnose operon transcriptional activator RhaRUniRule annotation
Gene namesi
Name:rhaRUniRule annotation
Ordered Locus Names:PC1_0422
OrganismiPectobacterium carotovorum subsp. carotovorum (strain PC1)
Taxonomic identifieri561230 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000002736 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002154031 – 284HTH-type transcriptional activator RhaRAdd BLAST284

Interactioni

Subunit structurei

Binds DNA as a dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei248Interaction with sigma-70UniRule annotation1

Protein-protein interaction databases

STRINGi561230.PC1_0422.

Structurei

3D structure databases

ProteinModelPortaliC6DJR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 2 HTH araC/xylS-type DNA-binding domains.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.
OrthoDBiPOG091H039M.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR014710. RmlC-like_jellyroll.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6DJR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAVRGLKL QTEDYFLTDK NVVMVAERHP QPVFPLHHHD FDELVIVWRG
60 70 80 90 100
NGLHLWNDVP YRITRGDMFY VSANDRHSYE SVHGLELDNI LYIRNRLTLS
110 120 130 140 150
ADWQRLLPGG EHPQSQRHWC LGSEGMDTLR EKVDALRQEC MKSDALSLQL
160 170 180 190 200
SEALLLQIAL LAARYRHTPD NPQLADAHQL DMLMNALRAS IAAPFRFEAF
210 220 230 240 250
CEQHHFSARS LRSRFKEQTG MSVPHYLRQL RLCKAMELLR YDLQTIGDIA
260 270 280
ALCGFEDSNY FSVVFHQAFG VSPSAYRQRF LNVE
Length:284
Mass (Da):32,839
Last modified:September 1, 2009 - v1
Checksum:i3D7E5367DE6D8597
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001657 Genomic DNA. Translation: ACT11478.1.
RefSeqiWP_012773134.1. NC_012917.1.

Genome annotation databases

EnsemblBacteriaiACT11478; ACT11478; PC1_0422.
KEGGipct:PC1_0422.
PATRICi20485416. VBIPecCar70489_0421.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001657 Genomic DNA. Translation: ACT11478.1.
RefSeqiWP_012773134.1. NC_012917.1.

3D structure databases

ProteinModelPortaliC6DJR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi561230.PC1_0422.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT11478; ACT11478; PC1_0422.
KEGGipct:PC1_0422.
PATRICi20485416. VBIPecCar70489_0421.

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.
OrthoDBiPOG091H039M.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR014710. RmlC-like_jellyroll.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRHAR_PECCP
AccessioniPrimary (citable) accession number: C6DJR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: November 30, 2016
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.