SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C6DHF6

- GPPA_PECCP

UniProt

C6DHF6 - GPPA_PECCP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase

Gene
gppA, PC1_4014
Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the "stringent response", an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities By similarity.UniRule annotation

Catalytic activityi

Guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. exopolyphosphatase activity Source: InterPro
  2. guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. guanosine pentaphosphate catabolic process Source: InterPro
  2. guanosine tetraphosphate biosynthetic process Source: UniProtKB-UniPathway
  3. polyphosphate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPCAR561230:GKCK-4106-MONOMER.
UniPathwayiUPA00908; UER00884.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC:3.6.1.40)
Alternative name(s):
Guanosine pentaphosphate phosphohydrolase
pppGpp-5'-phosphohydrolase
Gene namesi
Name:gppA
Ordered Locus Names:PC1_4014
OrganismiPectobacterium carotovorum subsp. carotovorum (strain PC1)
Taxonomic identifieri561230 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium
ProteomesiUP000002736: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 498498Guanosine-5'-triphosphate,3'-diphosphate pyrophosphataseUniRule annotationPRO_1000215466Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi561230.PC1_4014.

Structurei

3D structure databases

ProteinModelPortaliC6DHF6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0248.
HOGENOMiHOG000258672.
KOiK01524.
OMAiSYVHWAL.
OrthoDBiEOG6M6JN6.

Family and domain databases

HAMAPiMF_01550. GppA.
InterProiIPR022371. Exopolyphosphatase.
IPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view]
PfamiPF02541. Ppx-GppA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03706. exo_poly_only. 1 hit.

Sequencei

Sequence statusi: Complete.

C6DHF6-1 [UniParc]FASTAAdd to Basket

« Hide

MLSSSSLYAA IDLGSNSFHM LVARETAGSI QTLAKIKRKV RLAAGLDKQN    50
RLSQDAMQRG WQCLQLFSER LQDIPQDQVR VVATATLRLA TNADEFLQRA 100
QEILGLPIQV ISGEEEARLI YQGVAHTTGG PDARLVVDIG GGSTELATGV 150
GAKTTQLISL PMGCVTWLDR YFSDRNLEAG NFERAEQAAR EMLRPVAASL 200
REQGWQICVG ASGTVQALQE IMVAQGMDEY ITLPKLRQLK EHAIQCDKLE 250
ELEIEGLTLE RALVFPSGLA ILLAIFQELD IKTMTLAGGA LREGLVYGML 300
HLPVDQDIRH RTLATLQRRY LLDVEQAKRV STLADNFLQQ VARDWQLDNR 350
CRELLRSACL VHEIGLSIDF RQSPQHAAYL IRHSDLPGFT PAQKKLLATL 400
LQNQINPVDL MPLSQQNALP VNQAQRLCRL LRLAIIFASR RRDDTLPAVR 450
LRVEGETLRL ILPAGWLSQH PLRAEMLEQE SRWQSYVHWP LMLEETPA 498
Length:498
Mass (Da):55,777
Last modified:September 1, 2009 - v1
Checksum:i4B1670C7F306E724
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001657 Genomic DNA. Translation: ACT15029.1.
RefSeqiYP_003019565.1. NC_012917.1.

Genome annotation databases

EnsemblBacteriaiACT15029; ACT15029; PC1_4014.
GeneIDi8135005.
KEGGipct:PC1_4014.
PATRICi20492808. VBIPecCar70489_4043.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001657 Genomic DNA. Translation: ACT15029.1 .
RefSeqi YP_003019565.1. NC_012917.1.

3D structure databases

ProteinModelPortali C6DHF6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561230.PC1_4014.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT15029 ; ACT15029 ; PC1_4014 .
GeneIDi 8135005.
KEGGi pct:PC1_4014.
PATRICi 20492808. VBIPecCar70489_4043.

Phylogenomic databases

eggNOGi COG0248.
HOGENOMi HOG000258672.
KOi K01524.
OMAi SYVHWAL.
OrthoDBi EOG6M6JN6.

Enzyme and pathway databases

UniPathwayi UPA00908 ; UER00884 .
BioCyci PCAR561230:GKCK-4106-MONOMER.

Family and domain databases

HAMAPi MF_01550. GppA.
InterProi IPR022371. Exopolyphosphatase.
IPR023709. Guo-5TP_3DP_PyrP.
IPR003695. Ppx_GppA.
[Graphical view ]
Pfami PF02541. Ppx-GppA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03706. exo_poly_only. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.
    , Balakrishnan V., Glasner J., Perna N.T.
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PC1.

Entry informationi

Entry nameiGPPA_PECCP
AccessioniPrimary (citable) accession number: C6DHF6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: May 14, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi