rnr

Functionⁱ

3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.UniRule annotation

Catalytic activityⁱ

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functionⁱ

exoribonuclease II activity Source: UniProtKB-UniRule
RNA binding Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	ExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotation

Molecular function

ExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease, RNA-bindingUniRule annotation

Enzyme and pathway databases

BioCycⁱ	PCAR561230:G1GF8-3514-MONOMER.

BioCycⁱ

PCAR561230:G1GF8-3514-MONOMER.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ribonuclease RUniRule annotation (EC:3.1.13.1UniRule annotation) Short name: RNase RUniRule annotation
Gene namesⁱ	Name:rnrUniRule annotation Ordered Locus Names:PC1_3445Imported
Organismⁱ	Pectobacterium carotovorum subsp. carotovorum (strain PC1)Imported
Taxonomic identifierⁱ	561230 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Pectobacteriaceae › Pectobacterium › Pectobacterium carotovorum ›
Proteomesⁱ	UP000002736 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Automatic assertion according to rulesⁱ
- HAMAP-Rule:MF_01895
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00645091

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

CytoplasmUniRule annotationSAAS annotation

Interactionⁱ

Subunit structureⁱ

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGⁱ	561230.PC1_3445.

STRINGⁱ

561230.PC1_3445.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	C6DE25.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	641 – 722	S1 motifInterPro annotationAdd BLAST		82

Sequence similaritiesⁱ

Belongs to the RNR ribonuclease family. RNase R subfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105C40. Bacteria. COG0557. LUCA.
HOGENOMⁱ	HOG000071120.
KEGG Orthology (KO) More...KOⁱ	K12573.
OMAⁱ	DWYEYRS.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0219.

Family and domain databases

HAMAPⁱ	MF_01895. RNase_R. 1 hit.
InterProⁱ	View protein in InterPro IPR011129. CSD. IPR013223. RNase_B_OB_dom. IPR004476. RNase_II/RNase_R. IPR011805. RNase_R. IPR013668. RNase_R_HTH_12. IPR022967. S1_dom. IPR003029. S1_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08461. HTH_12. 1 hit. PF08206. OB_RNB. 2 hits. PF00575. S1. 1 hit.
SMARTⁱ	View protein in SMART SM00357. CSP. 1 hit. SM00316. S1. 1 hit.
TIGRFAMsⁱ	TIGR00358. 3_prime_RNase. 1 hit. TIGR02063. RNase_R. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50126. S1. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

C6DE25-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSQDPFLERE AEKYESPIPS REYILAHIAK RDTPISREEL AADLQLTGEE 
        60         70         80         90        100
PLEALRRRLR AMERDGQLIF TRRQCYALPE KLDLLRGTVI GHRDGFGFLR 
       110        120        130        140        150
VEGRKDDLYL SAEEMKRAIH GDVVLAQPLG ADRKGRREGR IVRVLEPRTG 
       160        170        180        190        200
QIVGRYFVDA GVGFVVPDDS RLSFDILIPK EEINGARMGF VVVVELTQRA 
       210        220        230        240        250
TRRTKAVGKI VEILGDNMGT GLAVDIALRT HDIPHTWPPK VEEQVKDLAE 
       260        270        280        290        300
EVPEAAKKGR VDLRKLPLVT IDGEDARDFD DAVYCEKKRG GGWRLWVAIA 
       310        320        330        340        350
DVSYYVRPNT PLDHEARARG TSVYFPSQVV PMLPEVLSNG LCSLNPQVDR 
       360        370        380        390        400
LCMVCEMTVS AQGKLSSYKF YEAVMSSHAR LTYTKVWNIL QGDAELREHY 
       410        420        430        440        450
KPLVGGLEEL HHMYKVLEHA REVRGGIAFE TEEAKFIFNA ERRIDRVEAV 
       460        470        480        490        500
VRNDAHKLIE ECMILANISA AKFVEKNEEP ALFRVHDQPS EDHVLALRSV 
       510        520        530        540        550
LGELGLTLKG GMKPQPKDYA ELMNEVADRP DREMLQTMLL RSMKQAIYDP 
       560        570        580        590        600
ENRGHFGLAL TSYGHFTSPI RRYPDLSLHR AIKYLLSNRH ERWTPTGGWH 
       610        620        630        640        650
SDINEMLQLG MHCSMTERRA DEATRDVADW LKCDFMQDHV GEVFTGIISS 
       660        670        680        690        700
VTGFGFFVRL KDLFIDGLVH VSTLDNDYYR YDNIGQRLIG ESRGQVYRLG 
       710        720        730        740        750
DEVEIRVEAV HMDERNIDFA LISSTRKVRG EGKTARDRAK KPDSREAKPA 
       760        770        780        790        800
RRRRSASKAP ANFEPDAAFR KEGDRNAKSD KPKAKPKKNR DKAKKNAEKT 
       810 
RKIAAATKAK RAKKKSAE

Length:818

Mass (Da):92,930

Last modified:September 1, 2009 - v1

Checksum:ⁱA2A653F19EA32096

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001657 Genomic DNA. Translation: ACT14461.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_015841586.1. NC_012917.1.

Genome annotation databases

EnsemblBacteriaⁱ	ACT14461; ACT14461; PC1_3445.
GeneIDⁱ	29704354.
KEGGⁱ	pct:PC1_3445.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
C6DE25	A0A0G4JW33 A0A0J5XL35 A0A2I1BHT3 A0A221T5U3 A0A1D7YXA8 A0A2D3MTL3 A0A0M2EWV5 A0A086EPV4 A0A093SP19 A0A0H3IA19 +37	Brenneria goodwinii Pectobacterium carotovorum subsp. carotovorum UGC32 Pectobacterium peruviense Pectobacterium carotovorum (Erwinia carotovora) Pectobacterium wasabiae CFBP 3304 Pectobacterium carotovorum subsp. brasiliense Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora) Pectobacterium sp. (strain SCC3193) Pectobacterium parmentieri (strain WPP163) (Pectobacterium wasabiae (strain WPP163)) Pectobacterium carotovorum subsp. odoriferum And more	818	UniRef90_A0A0G4JW33	Cluster: Ribonuclease R	48

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
C6DE25	A0A1N6MST5 UPI000B354CDC A0A2D0L633 UPI000C03A355 A0A2D0K8I7 UPI000C0496EE A0A2D0KTT7 UPI000C053E30 A0A2D0J4Z4 UPI000C052BCF +617	Xenorhabdus innexi Xenorhabdus sp. KJ12.1 Xenorhabdus sp. KK7.4 Xenorhabdus stockiae Xenorhabdus budapestensis Xenorhabdus cabanillasii JM26 Xenorhabdus cabanillasii Xenorhabdus sp. NBAII XenSa04 Pseudoalteromonas ulvae Colwellia sp. MT41 And more	844	UniRef50_A0A1N6MST5	Cluster: Ribonuclease R	628

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP001657 Genomic DNA. Translation: ACT14461.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_015841586.1. NC_012917.1.

3D structure databases

ProteinModelPortalⁱ	C6DE25.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	561230.PC1_3445.

STRINGⁱ

561230.PC1_3445.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ACT14461; ACT14461; PC1_3445.
GeneIDⁱ	29704354.
KEGGⁱ	pct:PC1_3445.

Phylogenomic databases

eggNOGⁱ	ENOG4105C40. Bacteria. COG0557. LUCA.
HOGENOMⁱ	HOG000071120.
KEGG Orthology (KO) More...KOⁱ	K12573.
OMAⁱ	DWYEYRS.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0219.

Enzyme and pathway databases

BioCycⁱ	PCAR561230:G1GF8-3514-MONOMER.

BioCycⁱ

PCAR561230:G1GF8-3514-MONOMER.

Family and domain databases

HAMAPⁱ	MF_01895. RNase_R. 1 hit.
InterProⁱ	View protein in InterPro IPR011129. CSD. IPR013223. RNase_B_OB_dom. IPR004476. RNase_II/RNase_R. IPR011805. RNase_R. IPR013668. RNase_R_HTH_12. IPR022967. S1_dom. IPR003029. S1_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08461. HTH_12. 1 hit. PF08206. OB_RNB. 2 hits. PF00575. S1. 1 hit.
SMARTⁱ	View protein in SMART SM00357. CSP. 1 hit. SM00316. S1. 1 hit.
TIGRFAMsⁱ	TIGR00358. 3_prime_RNase. 1 hit. TIGR02063. RNase_R. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50126. S1. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	C6DE25_PECCP
Accessionⁱ	C6DE25Primary (citable) accession number: C6DE25
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	September 1, 2009
	Last sequence update:	September 1, 2009
	Last modified:	February 28, 2018
	This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - C6DE25 (C6DE25_PECCP)

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Ribonuclease R

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Functionⁱ

Catalytic activityⁱ

GO - Molecular functionⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Subunit structureⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - C6DE25 (C6DE25_PECCP)

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Ribonuclease R

rnr

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ