Ribonuclease R

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>Describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the ‘Names and taxonomy’ section.</p><p><a href='../manual/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• exoribonuclease II activity Source: UniProtKB-HAMAP
• RNA binding Source: UniProtKB-HAMAP

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Molecular functionⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Ligandⁱ

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• cytoplasm Source: UniProtKB-SubCell

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>Provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="/help/function_section">‘Function’</a> section).</p><p><a href='../manual/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	641 – 722	82	S1 motifInterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50126			Add BLAST

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MSQDPFLERE AEKYESPIPS REYILAHIAK RDTPISREEL AADLQLTGEE 
        60         70         80         90        100
PLEALRRRLR AMERDGQLIF TRRQCYALPE KLDLLRGTVI GHRDGFGFLR 
       110        120        130        140        150
VEGRKDDLYL SAEEMKRAIH GDVVLAQPLG ADRKGRREGR IVRVLEPRTG 
       160        170        180        190        200
QIVGRYFVDA GVGFVVPDDS RLSFDILIPK EEINGARMGF VVVVELTQRA 
       210        220        230        240        250
TRRTKAVGKI VEILGDNMGT GLAVDIALRT HDIPHTWPPK VEEQVKDLAE 
       260        270        280        290        300
EVPEAAKKGR VDLRKLPLVT IDGEDARDFD DAVYCEKKRG GGWRLWVAIA 
       310        320        330        340        350
DVSYYVRPNT PLDHEARARG TSVYFPSQVV PMLPEVLSNG LCSLNPQVDR 
       360        370        380        390        400
LCMVCEMTVS AQGKLSSYKF YEAVMSSHAR LTYTKVWNIL QGDAELREHY 
       410        420        430        440        450
KPLVGGLEEL HHMYKVLEHA REVRGGIAFE TEEAKFIFNA ERRIDRVEAV 
       460        470        480        490        500
VRNDAHKLIE ECMILANISA AKFVEKNEEP ALFRVHDQPS EDHVLALRSV 
       510        520        530        540        550
LGELGLTLKG GMKPQPKDYA ELMNEVADRP DREMLQTMLL RSMKQAIYDP 
       560        570        580        590        600
ENRGHFGLAL TSYGHFTSPI RRYPDLSLHR AIKYLLSNRH ERWTPTGGWH 
       610        620        630        640        650
SDINEMLQLG MHCSMTERRA DEATRDVADW LKCDFMQDHV GEVFTGIISS 
       660        670        680        690        700
VTGFGFFVRL KDLFIDGLVH VSTLDNDYYR YDNIGQRLIG ESRGQVYRLG 
       710        720        730        740        750
DEVEIRVEAV HMDERNIDFA LISSTRKVRG EGKTARDRAK KPDSREAKPA 
       760        770        780        790        800
RRRRSASKAP ANFEPDAAFR KEGDRNAKSD KPKAKPKKNR DKAKKNAEKT 
       810 
RKIAAATKAK RAKKKSAE                                  

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ