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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:PC1_0640
OrganismiPectobacterium carotovorum subsp. carotovorum (strain PC1)
Taxonomic identifieri561230 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000002736 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002161121 – 311Ribosomal RNA large subunit methyltransferase FAdd BLAST311

Interactioni

Protein-protein interaction databases

STRINGi561230.PC1_0640.

Structurei

3D structure databases

ProteinModelPortaliC6D8Y7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiTEFHQGH.
OrthoDBiPOG091H05H4.

Family and domain databases

HAMAPiMF_01848. 23SrRNA_methyltr_F. 1 hit.
InterProiView protein in InterPro
IPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiView protein in Pfam
PF05971. Methyltransf_10. 1 hit.
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.

Sequencei

Sequence statusi: Complete.

C6D8Y7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKPAVQKNG LHPRNRHRDR YDFPTLKHSY PALIPFVTVN AYGDESVDFA
60 70 80 90 100
NPEAVKTLNQ ALLQHFYQIE HWEIPDGFLC PPIPGRADYI HHLADLLAED
110 120 130 140 150
NRAVVPREAS VLDIGCGANC IYPLIGYREY GWRFTGSEIN PIAMKAANQT
160 170 180 190 200
IEANPGLNRA IRLRRQKSST AILAGIIHKN ETFDAVMCNP PFHASAEDAR
210 220 230 240 250
QGSQRKLHNL GLDKRSPLNF GGQQDELWCE GGESAFIGQM IKESAGFARQ
260 270 280 290 300
CLWFTSLVSR KENLPEIYRA LEAVDAEKVR TIDMAQGQKQ SRFVAWSFLD
310
TAARTRWLQK R
Length:311
Mass (Da):35,159
Last modified:September 1, 2009 - v1
Checksum:i7AFA613D655A5F2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001657 Genomic DNA. Translation: ACT11695.1.
RefSeqiWP_012773342.1. NC_012917.1.

Genome annotation databases

EnsemblBacteriaiACT11695; ACT11695; PC1_0640.
GeneIDi29702490.
KEGGipct:PC1_0640.

Similar proteinsi

Entry informationi

Entry nameiRLMF_PECCP
AccessioniPrimary (citable) accession number: C6D8Y7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: August 30, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families