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C6D7U2

- C6D7U2_PAESJ

UniProt

C6D7U2 - C6D7U2_PAESJ

Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
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    Functioni

    Involved in phosphonate degradation.UniRule annotation

    Catalytic activityi

    Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

    Cofactori

    Binds 1 Mg2+ ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei9 – 91NucleophileUniRule annotation
    Metal bindingi9 – 91MagnesiumUniRule annotation
    Metal bindingi11 – 111Magnesium; via carbonyl oxygenUniRule annotation
    Active sitei50 – 501Schiff-base intermediate with substrateUniRule annotation
    Metal bindingi183 – 1831MagnesiumUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. organic phosphonate catabolic process Source: InterPro

    Keywords - Molecular functioni

    HydrolaseUniRule annotationImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Schiff baseUniRule annotation

    Enzyme and pathway databases

    BioCyciPSP324057:GH5H-4449-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
    Short name:
    PhosphonataseUniRule annotation
    Alternative name(s):
    Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
    Gene namesi
    Name:phnXUniRule annotation
    Ordered Locus Names:Pjdr2_4351Imported
    OrganismiPaenibacillus sp. (strain JDR-2)Imported
    Taxonomic identifieri324057 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
    ProteomesiUP000002510: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi324057.Pjdr2_4351.

    Structurei

    3D structure databases

    ProteinModelPortaliC6D7U2.
    SMRiC6D7U2. Positions 3-257.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0637.
    HOGENOMiHOG000217971.
    KOiK05306.
    OMAiTWPGILE.
    OrthoDBiEOG6ZH2FH.

    Family and domain databases

    Gene3Di1.10.150.240. 1 hit.
    3.40.50.1000. 2 hits.
    HAMAPiMF_01375. PhnX.
    InterProiIPR023214. HAD-like_dom.
    IPR023198. PGP_dom2.
    IPR006323. Phosphonoacetald_hydro.
    [Graphical view]
    PfamiPF13419. HAD_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01422. phosphonatase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6D7U2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMIKAVMLDW AGTMVDFGCF APLNVFVEVF ARKGVQVTVE EARQPMGMLK    50
    RDHIAAMCQM ERIAGVWEGL YGRKPGEADI DELYADFEPL LFSTLKDYAK 100
    PVPGAVELAD RLRSQGIAIG STTGYTRAMM DVVCKGAKEQ GYEPDTLVTP 150
    TEVSAGRPYP WMIYRNAEML GVYPMHHIVK AGDTVSDMLE GVNAGCWTVG 200
    VIVGSSELGM TEEEVNGCED AELSERKAAV AARLQAAGAH YVIDRIGQLD 250
    SLIAQINARM ERGERP 266
    Length:266
    Mass (Da):29,114
    Last modified:September 1, 2009 - v1
    Checksum:iBC81273470F1E237
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACT02972.1.
    RefSeqiWP_015845912.1. NC_012914.1.
    YP_003013058.1. NC_012914.1.

    Genome annotation databases

    EnsemblBacteriaiACT02972; ACT02972; Pjdr2_4351.
    GeneIDi8129082.
    KEGGipjd:Pjdr2_4351.
    PATRICi22839259. VBIPaeSp118865_4337.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACT02972.1 .
    RefSeqi WP_015845912.1. NC_012914.1.
    YP_003013058.1. NC_012914.1.

    3D structure databases

    ProteinModelPortali C6D7U2.
    SMRi C6D7U2. Positions 3-257.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 324057.Pjdr2_4351.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT02972 ; ACT02972 ; Pjdr2_4351 .
    GeneIDi 8129082.
    KEGGi pjd:Pjdr2_4351.
    PATRICi 22839259. VBIPaeSp118865_4337.

    Phylogenomic databases

    eggNOGi COG0637.
    HOGENOMi HOG000217971.
    KOi K05306.
    OMAi TWPGILE.
    OrthoDBi EOG6ZH2FH.

    Enzyme and pathway databases

    BioCyci PSP324057:GH5H-4449-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.240. 1 hit.
    3.40.50.1000. 2 hits.
    HAMAPi MF_01375. PhnX.
    InterProi IPR023214. HAD-like_dom.
    IPR023198. PGP_dom2.
    IPR006323. Phosphonoacetald_hydro.
    [Graphical view ]
    Pfami PF13419. HAD_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01422. phosphonatase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JDR-2Imported.

    Entry informationi

    Entry nameiC6D7U2_PAESJ
    AccessioniPrimary (citable) accession number: C6D7U2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3