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C6D7U2

- C6D7U2_PAESJ

UniProt

C6D7U2 - C6D7U2_PAESJ

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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91NucleophileUniRule annotation
Metal bindingi9 – 91MagnesiumUniRule annotation
Metal bindingi11 – 111Magnesium; via carbonyl oxygenUniRule annotation
Active sitei50 – 501Schiff-base intermediate with substrateUniRule annotation
Metal bindingi183 – 1831MagnesiumUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Schiff baseUniRule annotation

Enzyme and pathway databases

BioCyciPSP324057:GH5H-4449-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:Pjdr2_4351Imported
OrganismiPaenibacillus sp. (strain JDR-2)Imported
Taxonomic identifieri324057 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002510: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi324057.Pjdr2_4351.

Structurei

3D structure databases

ProteinModelPortaliC6D7U2.
SMRiC6D7U2. Positions 3-257.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000217971.
KOiK05306.
OMAiTWPGILE.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

C6D7U2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMIKAVMLDW AGTMVDFGCF APLNVFVEVF ARKGVQVTVE EARQPMGMLK
60 70 80 90 100
RDHIAAMCQM ERIAGVWEGL YGRKPGEADI DELYADFEPL LFSTLKDYAK
110 120 130 140 150
PVPGAVELAD RLRSQGIAIG STTGYTRAMM DVVCKGAKEQ GYEPDTLVTP
160 170 180 190 200
TEVSAGRPYP WMIYRNAEML GVYPMHHIVK AGDTVSDMLE GVNAGCWTVG
210 220 230 240 250
VIVGSSELGM TEEEVNGCED AELSERKAAV AARLQAAGAH YVIDRIGQLD
260
SLIAQINARM ERGERP
Length:266
Mass (Da):29,114
Last modified:September 1, 2009 - v1
Checksum:iBC81273470F1E237
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001656 Genomic DNA. Translation: ACT02972.1.
RefSeqiWP_015845912.1. NC_012914.1.
YP_003013058.1. NC_012914.1.

Genome annotation databases

EnsemblBacteriaiACT02972; ACT02972; Pjdr2_4351.
GeneIDi8129082.
KEGGipjd:Pjdr2_4351.
PATRICi22839259. VBIPaeSp118865_4337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001656 Genomic DNA. Translation: ACT02972.1 .
RefSeqi WP_015845912.1. NC_012914.1.
YP_003013058.1. NC_012914.1.

3D structure databases

ProteinModelPortali C6D7U2.
SMRi C6D7U2. Positions 3-257.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 324057.Pjdr2_4351.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT02972 ; ACT02972 ; Pjdr2_4351 .
GeneIDi 8129082.
KEGGi pjd:Pjdr2_4351.
PATRICi 22839259. VBIPaeSp118865_4337.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000217971.
KOi K05306.
OMAi TWPGILE.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci PSP324057:GH5H-4449-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JDR-2Imported.

Entry informationi

Entry nameiC6D7U2_PAESJ
AccessioniPrimary (citable) accession number: C6D7U2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3