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Protein

Thymidine kinase

Gene

Pjdr2_4014

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciPSP324057:GH5H-4111-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Pjdr2_4014Imported
OrganismiPaenibacillus sp. (strain JDR-2)Imported
Taxonomic identifieri324057 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002510 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi324057.Pjdr2_4014.

Structurei

3D structure databases

ProteinModelPortaliC6D5U9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OMAiVITGPMY.
OrthoDBiEOG69D3J2.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6D5U9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRGFITVII GPMFSEKSGE LIRRCQKLMK YGRKQVRAYK PAEDDRFSNE
60 70 80 90 100
EIVSRIGYRL PATSVPRALP ASSVEQILLE SKDADVVAFD EASFFGKPII
110 120 130 140 150
ALVEELAYQG KHIIVDGLNM DYRGKEFGYI GGLLAIADEI VKLTSFCAVC
160 170 180 190 200
GDANATFTQR IVNGKPAKLG PVFLIGDTES YEPRCRSCFV PPHKVTGDDA
210
EELTDTITAS QL
Length:212
Mass (Da):23,375
Last modified:September 1, 2009 - v1
Checksum:i9AA1A6ADD5561024
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001656 Genomic DNA. Translation: ACT02644.1.
RefSeqiWP_015845584.1. NC_012914.1.
YP_003012730.1. NC_012914.1.

Genome annotation databases

EnsemblBacteriaiACT02644; ACT02644; Pjdr2_4014.
KEGGipjd:Pjdr2_4014.
PATRICi22838577. VBIPaeSp118865_3998.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001656 Genomic DNA. Translation: ACT02644.1.
RefSeqiWP_015845584.1. NC_012914.1.
YP_003012730.1. NC_012914.1.

3D structure databases

ProteinModelPortaliC6D5U9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi324057.Pjdr2_4014.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT02644; ACT02644; Pjdr2_4014.
KEGGipjd:Pjdr2_4014.
PATRICi22838577. VBIPaeSp118865_3998.

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OMAiVITGPMY.
OrthoDBiEOG69D3J2.

Enzyme and pathway databases

BioCyciPSP324057:GH5H-4111-MONOMER.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JDR-2Imported.

Entry informationi

Entry nameiC6D5U9_PAESJ
AccessioniPrimary (citable) accession number: C6D5U9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 1, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.