C6D5J2 (C6D5J2_PAESJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023

Gene names

Name:	hisC2 HAMAP MF_01023
Ordered Locus Names:	Pjdr2_5865

Organism

Paenibacillus sp. (strain JDR-2) [Complete proteome] [HAMAP] EMBL ACT04469.1

Taxonomic identifier

324057 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Paenibacillaceae › Paenibacillus

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ACT04469.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	211	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	C6D5J2 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 7090B60BAAF6044F	FASTA	354	39,635
	10 20 30 40 50 60 MSKFWSPLTA SLVPYVPGEQ PKDKKYIKLN TNENPYPPSP QVLEAIRSVT NDDLRLYPDP 70 80 90 100 110 120 TCDALVRKIA GYFDVEPNRV FVGNGSDEVL AFAFAAFFNP AKPVAFADIT YSFYKVYAEF 130 140 150 160 170 180 YQLKADIIPL GEQFKLPVEE FSRRDTGGIV IPNPNAPTAM LISLDDIRTL LVQNPDQVVL 190 200 210 220 230 240 IDEAYIDFGG ESAAKLVNEY PNLLVVQTLS KSRSLAGLRV GWALGSEELI DGLNRVKNSF 250 260 270 280 290 300 NSYTLDRLAL AGAVAAFEDE AYFQETTAKV IATREAVTKE LKQLGFIVTD SAANFVFISH 310 320 330 340 350 PEHAAELLFQ QLRERGVLVR YFKQPRIDRY LRVTVGTDEE MAAFVEALKE IIKR

References

[1]

"Complete sequence of Paenibacillus sp. JDR-2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Shanmugam K.T., Ingram L.O., Preston J. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JDR-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001656 Genomic DNA. Translation: ACT04469.1.
RefSeq	YP_003014555.1. NC_012914.1.
3D structure databases
ProteinModelPortal	C6D5J2.
ModBase	Search...
Protein-protein interaction databases
STRING	C6D5J2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8128754.
GenomeReviews	Gene locus Pjdr2_5865 in contig CP001656_GR.
KEGG	pjd:Pjdr2_5865.
PATRIC	22842269. VBIPaeSp118865_5817.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MKNSFNS.
ProtClustDB	PRK05387.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C6D5J2_PAESJ

Accession

Primary (citable) accession number: C6D5J2

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)