Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C6D530 (C6D530_PAESJ) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Bifunctional protein PyrR HAMAP-Rule MF_01219
Gene names
Name:pyrR HAMAP-Rule MF_01219
Ordered Locus Names:Pjdr2_3865 EMBL ACT02495.1
OrganismPaenibacillus sp. (strain JDR-2) [Complete proteome] [HAMAP] EMBL ACT02495.1
Taxonomic identifier324057 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant By similarity. HAMAP-Rule MF_01219

Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes By similarity. HAMAP-Rule MF_01219

Catalytic activity

UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_01219 SAAS SAAS023050

Subunit structure

Homodimer and homohexamer; in equilibrium By similarity. HAMAP-Rule MF_01219

Sequence similarities

Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. HAMAP-Rule MF_01219

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif107 – 11913PRPP-binding By similarity HAMAP-Rule MF_01219

Sequences

Sequence LengthMass (Da)Tools
C6D530 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 80202698C9002072

FASTA19021,464
        10         20         30         40         50         60 
MEEEHLVIMD ETAIRRALTR IAHEIVEKNK GIDNCVLIGI RTRGIYLARR IADRIQDIEG 

        70         80         90        100        110        120 
KPVEVRELDI TSYRDDRKAA SVDTRVELAA VIGDLNGELF SAHDKKVILC DDVLFTGRTI 

       130        140        150        160        170        180 
RAAMDALMDC GRPESIQLAV LVDRGHRELP IRPDYVGKNV PTSKQEQIDV SLTEIDLKDQ 

       190 
VMIIHQRGQV 

« Hide

References

[1]"Complete genome sequence of Paenibacillus sp. strain JDR-2."
Chow V., Nong G., St John F.J., Rice J.D., Dickstein E., Chertkov O., Bruce D., Detter C., Brettin T., Han J., Woyke T., Pitluck S., Nolan M., Pati A., Martin J., Copeland A., Land M.L., Goodwin L. expand/collapse author list , Jones J.B., Ingram L.O., Shanmugam K.T., Preston J.F.
Stand. Genomic Sci. 6:1-10(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JDR-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001656 Genomic DNA. Translation: ACT02495.1.
RefSeqYP_003012581.1. NC_012914.1.

3D structure databases

ProteinModelPortalC6D530.
SMRC6D530. Positions 7-183.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING324057.Pjdr2_3865.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACT02495; ACT02495; Pjdr2_3865.
GeneID8126390.
KEGGpjd:Pjdr2_3865.
PATRIC22838265. VBIPaeSp118865_3846.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2065.
HOGENOMHOG000245770.
KOK02825.
OMARISHEIL.
OrthoDBEOG61VZD8.
ProtClustDBCLSK2551238.

Enzyme and pathway databases

BioCycPSP324057:GH5H-3958-MONOMER.

Family and domain databases

HAMAPMF_01219. PyrR.
InterProIPR000836. PRibTrfase_dom.
IPR023050. PyrR.
[Graphical view]
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6D530_PAESJ
AccessionPrimary (citable) accession number: C6D530
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)