SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C6D525

- C6D525_PAESJ

UniProt

C6D525 - C6D525_PAESJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Orotidine 5'-phosphate decarboxylase
Gene
pyrF, Pjdr2_3860
Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei17 – 171Substrate By similarityUniRule annotation
Binding sitei39 – 391Substrate By similarityUniRule annotation
Active sitei68 – 681Proton donor By similarityUniRule annotation
Binding sitei129 – 1291Substrate By similarityUniRule annotation
Binding sitei191 – 1911Substrate By similarityUniRule annotation
Binding sitei200 – 2001Substrate By similarityUniRule annotation
Binding sitei220 – 2201Substrate; via amide nitrogen By similarityUniRule annotation
Binding sitei221 – 2211Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Biological processi

Pyrimidine biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciPSP324057:GH5H-3953-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylaseUniRule annotation (EC:4.1.1.23UniRule annotation)
Alternative name(s):
OMP decarboxylase
Gene namesi
Name:pyrFUniRule annotation
Ordered Locus Names:Pjdr2_3860Imported
OrganismiPaenibacillus sp. (strain JDR-2)Imported
Taxonomic identifieri324057 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002510: Chromosome

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi324057.Pjdr2_3860.

Structurei

3D structure databases

ProteinModelPortaliC6D525.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni66 – 7510Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000226071.
KOiK01591.
OMAiSAYHAIK.
OrthoDBiEOG6N6815.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01200_B. OMPdecase_type1_B.
InterProiIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR01740. pyrF. 1 hit.
PROSITEiPS00156. OMPDECASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6D525-1 [UniParc]FASTAAdd to Basket

« Hide

MSLTREQAAG KVMVALDYAD AASAKRLLSE LEGIPCYMKV GMQLFYAAGP    50
SFVEELKKRG YRVFLDVKMH DIPNTVKGGS NSVTKLGVDM FNVHAAGGAA 100
MMEAAVEGAE AALASGQARP AIIAVTQLTS TNVQVLNEEI GIAGSVEQAV 150
VRYAELAKRA GLNGVVASPL EVDVIKSACG TSFQTVTPGI RPTWAATNDQ 200
SRIMTPREAL EQGTDYMVIG RPITAAASPR EALESIIEEL I 241
Length:241
Mass (Da):25,487
Last modified:September 1, 2009 - v1
Checksum:i741E997CE6A198B7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001656 Genomic DNA. Translation: ACT02490.1.
RefSeqiWP_015845430.1. NC_012914.1.
YP_003012576.1. NC_012914.1.

Genome annotation databases

EnsemblBacteriaiACT02490; ACT02490; Pjdr2_3860.
GeneIDi8126385.
KEGGipjd:Pjdr2_3860.
PATRICi22838255. VBIPaeSp118865_3841.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001656 Genomic DNA. Translation: ACT02490.1 .
RefSeqi WP_015845430.1. NC_012914.1.
YP_003012576.1. NC_012914.1.

3D structure databases

ProteinModelPortali C6D525.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 324057.Pjdr2_3860.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT02490 ; ACT02490 ; Pjdr2_3860 .
GeneIDi 8126385.
KEGGi pjd:Pjdr2_3860.
PATRICi 22838255. VBIPaeSp118865_3841.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000226071.
KOi K01591.
OMAi SAYHAIK.
OrthoDBi EOG6N6815.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci PSP324057:GH5H-3953-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01200_B. OMPdecase_type1_B.
InterProi IPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR01740. pyrF. 1 hit.
PROSITEi PS00156. OMPDECASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JDR-2.

Entry informationi

Entry nameiC6D525_PAESJ
AccessioniPrimary (citable) accession number: C6D525
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi