Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

Pjdr2_3753

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei322S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei349S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei368S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei421NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPSP324057:GH5H-3792-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:Pjdr2_3753Imported
OrganismiPaenibacillus sp. (strain JDR-2)Imported
Taxonomic identifieri324057 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
Proteomesi
  • UP000002510 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi324057.Pjdr2_3753.

Structurei

3D structure databases

ProteinModelPortaliC6D4F5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini208 – 490SAM_MT_RSMB_NOPInterPro annotationAdd BLAST283

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

C6D4F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSERETFKSR PKRKPGGKGH GRGPGQEGRK EQRPARVRTP RELALDTLVK
60 70 80 90 100
VAETGAYSNL QLNRVLQEAQ LQRADAALVT ELVYGTIQRQ LTLDHWLGKF
110 120 130 140 150
AAKGLRKLEP WVHQLLRMSA YQLLYLDRIP AHAAVNEAVT IAKRRGHQGI
160 170 180 190 200
SGMVNGILRS IDRNRAELTV DAIADKNPVV QISVRYSYPE WLVERWVKAY
210 220 230 240 250
GAETAEAICA SGNEPPHASV RVNPLRSSRN EVLSLLTEQG GDAEASRLAP
260 270 280 290 300
AGIVVRRGGN LADTEGFRDG LWTMQDESSM LVAEVVAPKA GMQVLDCCAA
310 320 330 340 350
PGGKTTHMAE LMSGKGKVYA NDLHPHKRQL IVDQAVRLGL QNIEAITEDA
360 370 380 390 400
GKLGERFAPA SIDAVLLDAP CSGFGVIRRK PEIKWTKTAG DVAEIAAIQR
410 420 430 440 450
RLLGAVAGLV KPGGTLVYST CTIESTENEE QVAVFLKEHP EFQLDAEWPE
460 470 480 490
EALAPLREKG IIDSSFDGQA QLLPHHYGSD GFFIARLRRR P
Length:491
Mass (Da):53,877
Last modified:September 1, 2009 - v1
Checksum:iD80853288FD5AAFD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001656 Genomic DNA. Translation: ACT02383.1.
RefSeqiWP_015845324.1. NC_012914.1.

Genome annotation databases

EnsemblBacteriaiACT02383; ACT02383; Pjdr2_3753.
KEGGipjd:Pjdr2_3753.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC6D4F5_PAESJ
AccessioniPrimary (citable) accession number: C6D4F5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: June 7, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported