C6CU28 (C6CU28_PAESJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Exodeoxyribonuclease 7 large subunit HAMAP-Rule MF_00378
EC=3.1.11.6 HAMAP-Rule MF_00378

Alternative name(s):
Exodeoxyribonuclease VII large subunit HAMAP-Rule MF_00378

Gene names

Name:	xseA HAMAP-Rule MF_00378
Ordered Locus Names:	Pjdr2_2309

Organism

Paenibacillus sp. (strain JDR-2) [Complete proteome] [HAMAP] EMBL ACT00965.1

Taxonomic identifier

324057 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00378 SAAS SAAS020579
Catalytic activity	Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00378 Exonucleolytic cleavage in either 5'- to 3'-or 3'- to 5'-direction to yield nucleoside 5'-phosphates. SAAS SAAS020579
Subunit structure	Heterooligomer composed of large and small subunits By similarity. HAMAP-Rule MF_00378 SAAS SAAS020579
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00378 SAAS SAAS020579.
Sequence similarities	Belongs to the XseA family. HAMAP-Rule MF_00378

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00378 SAAS SAAS020579
Molecular function	Exonuclease HAMAP-Rule MF_00378 SAAS SAAS020579 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA catabolic process Inferred from electronic annotation. Source: HAMAP nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exodeoxyribonuclease VII complex Inferred from electronic annotation. Source: InterPro
Molecular_function	exodeoxyribonuclease VII activity Inferred from electronic annotation. Source: HAMAP nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6CU28 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 13AC1774FAE96B46	FASTA	457	51,711
	10 20 30 40 50 60 MADQPRIYSI KDINRYIRMK LESDVLLSDV WLRGEISNFT HHSSGHMYFT LKDKDSRLKC 70 80 90 100 110 120 IMFASHNQRL PFIPREGTKV MARGNVSVYE RDGNYQFYVT AMQPDGIGSL YLAYEQLKSK 130 140 150 160 170 180 LETEGLFAES RKRPIPRFPR AIGVITSPTG AAVRDIITTL QRRHPSIPIY VFPVLVQGTQ 190 200 210 220 230 240 AAPSIVKAIE SMNRFGEVDV LIVGRGGGSL EELWAFNEEP VARSIAASQI PVISAVGHET 250 260 270 280 290 300 DFTIADFVAD LRAATPTAAA ELAVPHIAEL QQQLARQRQR LEQSLRMMVQ GRKEQLQRVR 310 320 330 340 350 360 RSPFFVHPRK YLLDQAQRLD RLQERLQHRT LRLTERGKAK LERLQSQLAG HHPGEQAAFA 370 380 390 400 410 420 AKRLQGDVKR LEQAMVSSLK ERRLQLQSAI RQLDALSPLK VMARGYSLVY DEQEKRLIKS 430 440 450 IADVQPGDLV RVKVADGQLD CHVWSMKGED GVESSGE

References

[1]

"Complete genome sequence of Paenibacillus sp. strain JDR-2." Chow V., Nong G., St John F.J., Rice J.D., Dickstein E., Chertkov O., Bruce D., Detter C., Brettin T., Han J., Woyke T., Pitluck S., Nolan M., Pati A., Martin J., Copeland A., Land M.L., Goodwin L. , Jones J.B., Ingram L.O., Shanmugam K.T., Preston J.F. Stand. Genomic Sci. 6:1-10(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JDR-2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001656 Genomic DNA. Translation: ACT00965.1.
RefSeq	YP_003011051.1. NC_012914.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	324057.Pjdr2_2309.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT00965; ACT00965; Pjdr2_2309.
GeneID	8124180.
KEGG	pjd:Pjdr2_2309.
PATRIC	22835125. VBIPaeSp118865_2284.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1570.
HOGENOM	HOG000229265.
KO	K03601.
OMA	SSQIRCA.
ProtClustDB	CLSK2550840.
Enzyme and pathway databases
BioCyc	PSP324057:GH5H-2395-MONOMER.
Family and domain databases
HAMAP	MF_00378. Exonuc_7_L.
InterPro	IPR003753. Exonuc_VII_L. IPR020579. Exonuc_VII_lsu_C. IPR025824. OB-fold_nuc-bd_dom. [Graphical view]
Pfam	PF02601. Exonuc_VII_L. 1 hit. PF13742. tRNA_anti_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR00237. xseA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6CU28_PAESJ

Accession

Primary (citable) accession number: C6CU28

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 1, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)