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Protein

DNA polymerase III subunit beta

Gene

Pjdr2_0002

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.UniRule annotation

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotationSAAS annotation

GO - Molecular functioni

  1. 3'-5' exonuclease activity Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA-directed DNA polymerase activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymeraseUniRule annotationSAAS annotation, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replicationUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPSP324057:GH5H-2-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase III subunit betaUniRule annotationSAAS annotation (EC:2.7.7.7UniRule annotationSAAS annotation)
Gene namesi
Ordered Locus Names:Pjdr2_0002Imported
OrganismiPaenibacillus sp. (strain JDR-2)Imported
Taxonomic identifieri324057 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
ProteomesiUP000002510 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. DNA polymerase III complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi324057.Pjdr2_0002.

Structurei

3D structure databases

ProteinModelPortaliC6CSZ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0592.
HOGENOMiHOG000071792.
KOiK02338.
OMAiIAFNVRY.
OrthoDBiEOG65J53F.

Family and domain databases

InterProiIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamiPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00663. dnan. 1 hit.

Sequencei

Sequence statusi: Complete.

C6CSZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSISKHEL NEAIQQVAKA ASSRPTIPIL GGIKIEVTHQ GVTLTASDTD
60 70 80 90 100
ISIQSFIPVE RDDLVIANVD KPGNVVLPAK FFVEIVKKLP SDNVEIEVGA
110 120 130 140 150
HFQTLIRSGS TDIQMVGLDP EEFPVLPSIE QNELFQMPGD LLKAMIRQTV
160 170 180 190 200
LAASVNEQTP ILTGVLWSLQ DKQLKFVATD RHRLASRIAQ AETAADYRFN
210 220 230 240 250
NVVIAAKTLV ELSKLVPDQH GLVDIVVADN QVLFKIGNVL FYTRVLDGTY
260 270 280 290 300
PDTSKIIPSV FKTELVLDTK KLTDAIDRAY LMSREEKTNI VRLATMEDGS
310 320 330 340 350
IEISSSSTEL GRVTEQLEPK QFDGEPLKIA FNSKYMLDVL KVIDSEHIFI
360 370 380
GFTGAMSPIV IRPTDHSYNT YVILPYRTTN
Length:380
Mass (Da):42,147
Last modified:August 31, 2009 - v1
Checksum:i80AA5D725055C77C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001656 Genomic DNA. Translation: ACS98682.1.
RefSeqiWP_012772004.1. NC_012914.1.
YP_003008769.1. NC_012914.1.

Genome annotation databases

EnsemblBacteriaiACS98682; ACS98682; Pjdr2_0002.
KEGGipjd:Pjdr2_0002.
PATRICi22830395. VBIPaeSp118865_0002.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001656 Genomic DNA. Translation: ACS98682.1.
RefSeqiWP_012772004.1. NC_012914.1.
YP_003008769.1. NC_012914.1.

3D structure databases

ProteinModelPortaliC6CSZ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi324057.Pjdr2_0002.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS98682; ACS98682; Pjdr2_0002.
KEGGipjd:Pjdr2_0002.
PATRICi22830395. VBIPaeSp118865_0002.

Phylogenomic databases

eggNOGiCOG0592.
HOGENOMiHOG000071792.
KOiK02338.
OMAiIAFNVRY.
OrthoDBiEOG65J53F.

Enzyme and pathway databases

BioCyciPSP324057:GH5H-2-MONOMER.

Family and domain databases

InterProiIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamiPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00663. dnan. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JDR-2Imported.

Entry informationi

Entry nameiC6CSZ8_PAESJ
AccessioniPrimary (citable) accession number: C6CSZ8
Entry historyi
Integrated into UniProtKB/TrEMBL: August 31, 2009
Last sequence update: August 31, 2009
Last modified: March 31, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.