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C6CSZ8

- C6CSZ8_PAESJ

UniProt

C6CSZ8 - C6CSZ8_PAESJ

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Protein
DNA polymerase III subunit beta
Gene
Pjdr2_0002
Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA By similarity.UniRule annotation

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).UniRule annotationSAAS annotations

GO - Molecular functioni

  1. 3'-5' exonuclease activity Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA-directed DNA polymerase activity Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    DNA-directed DNA polymeraseUniRule annotationSAAS annotations, Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    DNA replicationUniRule annotationSAAS annotations

    Enzyme and pathway databases

    BioCyciPSP324057:GH5H-2-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA polymerase III subunit betaUniRule annotation (EC:2.7.7.7UniRule annotation)
    Gene namesi
    Ordered Locus Names:Pjdr2_0002Imported
    OrganismiPaenibacillus sp. (strain JDR-2)Imported
    Taxonomic identifieri324057 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
    ProteomesiUP000002510: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotationSAAS annotations

    GO - Cellular componenti

    1. DNA polymerase III complex Source: InterPro
    2. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotations

    Interactioni

    Protein-protein interaction databases

    STRINGi324057.Pjdr2_0002.

    Structurei

    3D structure databases

    ProteinModelPortaliC6CSZ8.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0592.
    HOGENOMiHOG000071792.
    KOiK02338.
    OMAiSHEGRNN.
    OrthoDBiEOG65J53F.

    Family and domain databases

    InterProiIPR001001. DNA_polIII_beta.
    IPR022635. DNA_polIII_beta_C.
    IPR022637. DNA_polIII_beta_cen.
    IPR022634. DNA_polIII_beta_N.
    [Graphical view]
    PfamiPF00712. DNA_pol3_beta. 1 hit.
    PF02767. DNA_pol3_beta_2. 1 hit.
    PF02768. DNA_pol3_beta_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
    SMARTiSM00480. POL3Bc. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00663. dnan. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6CSZ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLSISKHEL NEAIQQVAKA ASSRPTIPIL GGIKIEVTHQ GVTLTASDTD    50
    ISIQSFIPVE RDDLVIANVD KPGNVVLPAK FFVEIVKKLP SDNVEIEVGA 100
    HFQTLIRSGS TDIQMVGLDP EEFPVLPSIE QNELFQMPGD LLKAMIRQTV 150
    LAASVNEQTP ILTGVLWSLQ DKQLKFVATD RHRLASRIAQ AETAADYRFN 200
    NVVIAAKTLV ELSKLVPDQH GLVDIVVADN QVLFKIGNVL FYTRVLDGTY 250
    PDTSKIIPSV FKTELVLDTK KLTDAIDRAY LMSREEKTNI VRLATMEDGS 300
    IEISSSSTEL GRVTEQLEPK QFDGEPLKIA FNSKYMLDVL KVIDSEHIFI 350
    GFTGAMSPIV IRPTDHSYNT YVILPYRTTN 380
    Length:380
    Mass (Da):42,147
    Last modified:September 1, 2009 - v1
    Checksum:i80AA5D725055C77C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACS98682.1.
    RefSeqiWP_012772004.1. NC_012914.1.
    YP_003008769.1. NC_012914.1.

    Genome annotation databases

    EnsemblBacteriaiACS98682; ACS98682; Pjdr2_0002.
    GeneIDi8126975.
    KEGGipjd:Pjdr2_0002.
    PATRICi22830395. VBIPaeSp118865_0002.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACS98682.1 .
    RefSeqi WP_012772004.1. NC_012914.1.
    YP_003008769.1. NC_012914.1.

    3D structure databases

    ProteinModelPortali C6CSZ8.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 324057.Pjdr2_0002.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACS98682 ; ACS98682 ; Pjdr2_0002 .
    GeneIDi 8126975.
    KEGGi pjd:Pjdr2_0002.
    PATRICi 22830395. VBIPaeSp118865_0002.

    Phylogenomic databases

    eggNOGi COG0592.
    HOGENOMi HOG000071792.
    KOi K02338.
    OMAi SHEGRNN.
    OrthoDBi EOG65J53F.

    Enzyme and pathway databases

    BioCyci PSP324057:GH5H-2-MONOMER.

    Family and domain databases

    InterProi IPR001001. DNA_polIII_beta.
    IPR022635. DNA_polIII_beta_C.
    IPR022637. DNA_polIII_beta_cen.
    IPR022634. DNA_polIII_beta_N.
    [Graphical view ]
    Pfami PF00712. DNA_pol3_beta. 1 hit.
    PF02767. DNA_pol3_beta_2. 1 hit.
    PF02768. DNA_pol3_beta_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000804. DNA_pol_III_b. 1 hit.
    SMARTi SM00480. POL3Bc. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00663. dnan. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JDR-2.

    Entry informationi

    Entry nameiC6CSZ8_PAESJ
    AccessioniPrimary (citable) accession number: C6CSZ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: September 3, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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