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C6CST1

- C6CST1_PAESJ

UniProt

C6CST1 - C6CST1_PAESJ

Protein

Transcription termination factor Rho

Gene

rho

Organism
Paenibacillus sp. (strain JDR-2)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
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    Functioni

    Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei210 – 2101ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi167 – 1726ATPUniRule annotation
    Nucleotide bindingi179 – 1846ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. helicase activity Source: UniProtKB-HAMAP
    3. RNA binding Source: UniProtKB-HAMAP
    4. RNA-dependent ATPase activity Source: InterPro

    GO - Biological processi

    1. DNA-templated transcription, termination Source: UniProtKB-HAMAP
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    HelicaseUniRule annotation, Hydrolase

    Keywords - Biological processi

    Transcription, Transcription regulation, Transcription terminationUniRule annotation

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding, RNA-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciPSP324057:GH5H-151-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription termination factor RhoUniRule annotation (EC:3.6.4.-UniRule annotation)
    Alternative name(s):
    ATP-dependent helicase RhoUniRule annotation
    Gene namesi
    Name:rhoUniRule annotation
    Ordered Locus Names:Pjdr2_0140Imported
    OrganismiPaenibacillus sp. (strain JDR-2)Imported
    Taxonomic identifieri324057 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus
    ProteomesiUP000002510: Chromosome

    Interactioni

    Subunit structurei

    Homohexamer. The homohexamer assembles into an open ring structure.UniRule annotation

    Protein-protein interaction databases

    STRINGi324057.Pjdr2_0140.

    Structurei

    3D structure databases

    ProteinModelPortaliC6CST1.
    SMRiC6CST1. Positions 56-409.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Rho family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1158.
    HOGENOMiHOG000076952.
    KOiK03628.
    OMAiEFMREKM.
    OrthoDBiEOG6N681W.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_01884. Rho.
    InterProiIPR003593. AAA+_ATPase.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR011129. Cold_shock_prot.
    IPR012340. NA-bd_OB-fold.
    IPR027417. P-loop_NTPase.
    IPR011112. Rho_N.
    IPR011113. Rho_RNA-bd.
    IPR004665. Term_rho.
    [Graphical view]
    PfamiPF00006. ATP-synt_ab. 1 hit.
    PF07498. Rho_N. 1 hit.
    PF07497. Rho_RNA_bind. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00357. CSP. 1 hit.
    SM00959. Rho_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF68912. SSF68912. 1 hit.
    TIGRFAMsiTIGR00767. rho. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6CST1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDLQISDLE EMKLTELYKL AKQYQIPYYG QLKKKELIFA ILRAQAEKSG    50
    LMFMQGVLET LPEGFGFLRP INYLPSKEDI YISASQIRKF DLRTGDLVSG 100
    KCRLPKDSEK YFGLLQVNAV NGTDPAQAAE RLHFPALTPL YPQKKLVLET 150
    ASSKLSTRIM DLLAPVGLGQ RGLIVAPPKA GKTLLLKEIA NSISTNHPDI 200
    ELFVLLIDER PEEVTDMQRS VKGEVIASTF DEVPENHIKV AELVLERALR 250
    LVEHKKDVVI LLDSITRLAR AYNLVVPPSG RTLSGGIDPA AFHRPKRFFG 300
    AARNVEEGGS LTILATALIE TGSRMDDIIY EEFKGTGNME LHLDRKLAER 350
    RIFPALDIRR SGTRREEMLL SKEELDKLWV VRRNMTDTPD FVDGFLKKLA 400
    DSKTNEEFLM SLDTSEEKPA PQQRTSTGTG LKSSAATGRR PAPRTTHGS 449
    Length:449
    Mass (Da):50,231
    Last modified:September 1, 2009 - v1
    Checksum:i335223FC9B79B657
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACS98820.1.
    RefSeqiWP_012772142.1. NC_012914.1.
    YP_003008907.1. NC_012914.1.

    Genome annotation databases

    EnsemblBacteriaiACS98820; ACS98820; Pjdr2_0140.
    GeneIDi8129237.
    KEGGipjd:Pjdr2_0140.
    PATRICi22830697. VBIPaeSp118865_0142.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001656 Genomic DNA. Translation: ACS98820.1 .
    RefSeqi WP_012772142.1. NC_012914.1.
    YP_003008907.1. NC_012914.1.

    3D structure databases

    ProteinModelPortali C6CST1.
    SMRi C6CST1. Positions 56-409.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 324057.Pjdr2_0140.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACS98820 ; ACS98820 ; Pjdr2_0140 .
    GeneIDi 8129237.
    KEGGi pjd:Pjdr2_0140.
    PATRICi 22830697. VBIPaeSp118865_0142.

    Phylogenomic databases

    eggNOGi COG1158.
    HOGENOMi HOG000076952.
    KOi K03628.
    OMAi EFMREKM.
    OrthoDBi EOG6N681W.

    Enzyme and pathway databases

    BioCyci PSP324057:GH5H-151-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_01884. Rho.
    InterProi IPR003593. AAA+_ATPase.
    IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
    IPR011129. Cold_shock_prot.
    IPR012340. NA-bd_OB-fold.
    IPR027417. P-loop_NTPase.
    IPR011112. Rho_N.
    IPR011113. Rho_RNA-bd.
    IPR004665. Term_rho.
    [Graphical view ]
    Pfami PF00006. ATP-synt_ab. 1 hit.
    PF07498. Rho_N. 1 hit.
    PF07497. Rho_RNA_bind. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00357. CSP. 1 hit.
    SM00959. Rho_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF68912. SSF68912. 1 hit.
    TIGRFAMsi TIGR00767. rho. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JDR-2Imported.

    Entry informationi

    Entry nameiC6CST1_PAESJ
    AccessioniPrimary (citable) accession number: C6CST1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3