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C6CSS1 (C6CSS1_PAESJ) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Spermidine synthase HAMAP-Rule MF_00198 RuleBase RU003837
EC=2.5.1.16 HAMAP-Rule MF_00198 RuleBase RU003837
Alternative name(s):
Putrescine aminopropyltransferase HAMAP-Rule MF_00198
SPDSY HAMAP-Rule MF_00198
Gene names
Name:speE HAMAP-Rule MF_00198
Ordered Locus Names:Pjdr2_0131
OrganismPaenibacillus sp. (strain JDR-2) [Complete proteome] [HAMAP] EMBL ACS98811.1
Taxonomic identifier324057 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Paenibacillaceae › Paenibacillus

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor By similarity. HAMAP-Rule MF_00198

Catalytic activity

S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine. HAMAP-Rule MF_00198 RuleBase RU003837

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1. HAMAP-Rule MF_00198

Subunit structure

Homodimer or homotetramer By similarity. HAMAP-Rule MF_00198

Sequence similarities

Belongs to the spermidine/spermine synthase family. HAMAP-Rule MF_00198 RuleBase RU003836

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region137 – 1382S-adenosylmethioninamine binding By similarity HAMAP-Rule MF_00198

Sites

Active site1551Proton acceptor By similarity HAMAP-Rule MF_00198
Binding site311S-adenosylmethioninamine By similarity HAMAP-Rule MF_00198
Binding site611Putrescine By similarity HAMAP-Rule MF_00198
Binding site861S-adenosylmethioninamine By similarity HAMAP-Rule MF_00198
Binding site1061S-adenosylmethioninamine By similarity HAMAP-Rule MF_00198
Binding site1581Putrescine By similarity HAMAP-Rule MF_00198
Binding site2231Putrescine By similarity HAMAP-Rule MF_00198

Sequences

Sequence LengthMass (Da)Tools
C6CSS1 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 07A5BEC8919FB8A2

FASTA27531,270
        10         20         30         40         50         60 
MELWYTEKQT ENFGITAKIT KTYVNEQTEF QQLDMIETEE FGTMLVLDGM VMTTVKDEFV 

        70         80         90        100        110        120 
YHEMVAHPVL FTHPNPEHVL VVGGGDGGVI REIMKHPKVK KAVLVDIDGK VIEYSKKYLP 

       130        140        150        160        170        180 
TIAGELDNPR VEVLVNDGFM HIHDHKNTYD VIMVDSTEPV GPAANLFTRG FYQGIYEALK 

       190        200        210        220        230        240 
EDGIFVAQTD NPWFKADLIQ SVNKDVKEVF PIVRVYGANI PTYPSGLWTF TMGSKKYDPL 

       250        260        270 
EVDEASITEI PTKYYTPRLH KAAFVLPKFV EDLVK

« Hide

References

[1]"Complete genome sequence of Paenibacillus sp. strain JDR-2."
Chow V., Nong G., St John F.J., Rice J.D., Dickstein E., Chertkov O., Bruce D., Detter C., Brettin T., Han J., Woyke T., Pitluck S., Nolan M., Pati A., Martin J., Copeland A., Land M.L., Goodwin L. expand/collapse author list , Jones J.B., Ingram L.O., Shanmugam K.T., Preston J.F.
Stand. Genomic Sci. 6:1-10(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JDR-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001656 Genomic DNA. Translation: ACS98811.1.
RefSeqYP_003008898.1. NC_012914.1.

3D structure databases

ProteinModelPortalC6CSS1.
SMRC6CSS1. Positions 2-274.
ModBaseSearch...

Protein-protein interaction databases

STRING324057.Pjdr2_0131.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS98811; ACS98811; Pjdr2_0131.
GeneID8129228.
KEGGpjd:Pjdr2_0131.
PATRIC22830677. VBIPaeSp118865_0132.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0421.
HOGENOMHOG000256146.
KOK00797.
OMAELWYTEK.
ProtClustDBCLSK2550307.

Enzyme and pathway databases

BioCycPSP324057:GH5H-142-MONOMER.
UniPathwayUPA00248; UER00314.

Family and domain databases

HAMAPMF_00198. Spermidine_synth.
InterProIPR001045. Spermidine/spermine_synthase.
[Graphical view]
PANTHERPTHR11558. PTHR11558. 1 hit.
PfamPF01564. Spermine_synth. 1 hit.
[Graphical view]
TIGRFAMsTIGR00417. speE. 1 hit.
PROSITEPS01330. SPERMIDINE_SYNTHASE_1. 1 hit.
PS51006. SPERMIDINE_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6CSS1_PAESJ
AccessionPrimary (citable) accession number: C6CSS1
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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