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C6CN33

- C6CN33_DICZE

UniProt

C6CN33 - C6CN33_DICZE

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Protein

Beta-galactosidase

Gene
lacZ, Dd1591_2733
Organism
Dickeya zeae (strain Ech1591)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotationSAAS annotations

Cofactori

Binds 1 sodium ion per monomer By similarity.UniRule annotation
Binds 2 magnesium ions per monomer By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei110 – 1101Substrate By similarityUniRule annotation
Metal bindingi209 – 2091Sodium By similarityUniRule annotation
Binding sitei209 – 2091Substrate By similarityUniRule annotation
Sitei366 – 3661Transition state stabilizer By similarityUniRule annotation
Sitei400 – 4001Transition state stabilizer By similarityUniRule annotation
Metal bindingi425 – 4251Magnesium 1 By similarityUniRule annotation
Metal bindingi427 – 4271Magnesium 1 By similarityUniRule annotation
Active sitei470 – 4701Proton donor By similarityUniRule annotation
Metal bindingi470 – 4701Magnesium 1 By similarityUniRule annotation
Binding sitei470 – 4701Substrate By similarityUniRule annotation
Active sitei546 – 5461Nucleophile By similarityUniRule annotation
Metal bindingi605 – 6051Magnesium 2 By similarityUniRule annotation
Metal bindingi609 – 6091Sodium; via carbonyl oxygen By similarityUniRule annotation
Metal bindingi612 – 6121Sodium By similarityUniRule annotation
Binding sitei612 – 6121Substrate By similarityUniRule annotation
Binding sitei1012 – 10121Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro
  3. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotations, Hydrolase

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation, SodiumUniRule annotation

Enzyme and pathway databases

BioCyciDZEA561229:GJ85-2791-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Short name:
Beta-galUniRule annotation
Alternative name(s):
Lactase
Gene namesi
Name:lacZUniRule annotation
Ordered Locus Names:Dd1591_2733Imported
OrganismiDickeya zeae (strain Ech1591)Imported
Taxonomic identifieri561229 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
ProteomesiUP000002735: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi561229.Dd1591_2733.

Structurei

3D structure databases

ProteinModelPortaliC6CN33.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni546 – 5494Substrate binding By similarityUniRule annotation

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000252443.
KOiK01190.
OMAiNPPFVPK.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_01687. Beta_gal.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023933. Glyco_hydro_2_beta_Galsidase.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6CN33-1 [UniParc]FASTAAdd to Basket

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MSTASAYAPL SGLSLADILA RRDWENPACP HIRRLDAHPP FSSWRNLNAA     50
RDDQPSDRRQ MLNGEWTFSY FSRPEAVPEQ WLTQDLTDAN PLAVPSNWQL 100
AGYDAPIYTN IKYPIPVNPP FVPQDNPTGC YSLTFSVNGD WLTQGQTRIV 150
FDGVNSAFHL WCNGQWVGYS QDSRLPAEFD LTSCLQPGEN RLAVMVLRWS 200
DGTYLEDQDM WRMSGIYRDV YLLHKPAVHL RDVQLTTPLR HSYTQGTLCV 250
TALANLPEDQ AQAWQLAVQL WRGGQLVGEQ RAPFGTPAID ERGAYHDRVS 300
LQLEVAQPAL WSAEEPNLYR AVVALEYDGT LVEAEAYDVG FREVAIRNGL 350
LLLNGQPLLI RGTNRHEHHP QYGQAIDEAT MRQDILLMKQ HNFNAVRCSH 400
YPNHPLWYRL CDRYGLYVVD EANIETHGMQ PMSRLSDDPR WLPAYAERVT 450
RMVQRDRNHP CIIIWSLGNE SGYGPTHSAL YQWVKQQDPT RPVQYEGGGA 500
DTPATDILCP MYARVDQDQP FPAVPKWSIK KWIGLPGEHR PLILCEYAHA 550
MGNSFGGFDR YWQAFRQYPR LQGGFVWDWV DQALTREQDG KTHWAYGGDF 600
GDKPNDRQFC LNGLVFPDRT PHPALYEAQR AQQFFQFNHH ENAPLTLTIT 650
SEYLFRRSDN EELHWRIMQD DVQLASGRVP LDITPQGCQT LTLLEQLPAP 700
QHHADMWLTV EVIQPNATDW SPAGHRCAWD QWQLPMPLAR PTPRRDGSER 750
PTLTQNDDQF EVIHGQQRWA FNRHNGLLTQ WWRDGQAQLL SPLQDNLARA 800
PLDNDIGISE VDRIDPNAWV ERWKLAGLYR YDTDCRHIHA DTLSDGVLIT 850
TEHIGHYQQQ VLFISRKQWR IDAQGVLTVS VEVDVARHLP SLARVGLSMQ 900
LAAVTPQVSW LGLGPHENYP DRRLAALHGR WQQPLEAMHT PYIFPSENGL 950
RCHTRELRYG DWLIEGDFHF GIGRYSRQQL MDCTHHHLLQ PEPGTWLNLD 1000
GFHMGIGGDD SWSPSVAPDF LLTAPRYRYQ LQLQLR 1036
Length:1,036
Mass (Da):118,909
Last modified:September 1, 2009 - v1
Checksum:iA8794CDE12419D1C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001655 Genomic DNA. Translation: ACT07558.1.
RefSeqiWP_012770413.1. NC_012912.1.
YP_003005037.1. NC_012912.1.

Genome annotation databases

EnsemblBacteriaiACT07558; ACT07558; Dd1591_2733.
GeneIDi8119175.
KEGGidze:Dd1591_2733.
PATRICi21801475. VBIDicZea111179_2781.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001655 Genomic DNA. Translation: ACT07558.1 .
RefSeqi WP_012770413.1. NC_012912.1.
YP_003005037.1. NC_012912.1.

3D structure databases

ProteinModelPortali C6CN33.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 561229.Dd1591_2733.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT07558 ; ACT07558 ; Dd1591_2733 .
GeneIDi 8119175.
KEGGi dze:Dd1591_2733.
PATRICi 21801475. VBIDicZea111179_2781.

Phylogenomic databases

eggNOGi COG3250.
HOGENOMi HOG000252443.
KOi K01190.
OMAi NPPFVPK.
OrthoDBi EOG6XWV0T.

Enzyme and pathway databases

BioCyci DZEA561229:GJ85-2791-MONOMER.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_01687. Beta_gal.
InterProi IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023933. Glyco_hydro_2_beta_Galsidase.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SMARTi SM01038. Bgal_small_N. 1 hit.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ech1591Imported.

Entry informationi

Entry nameiC6CN33_DICZE
AccessioniPrimary (citable) accession number: C6CN33
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 3, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi