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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Dickeya paradisiaca (strain Ech703) (Dickeya dadantii (strain Ech703))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotationImported, Hydrolase, Nuclease
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotation
Ordered Locus Names:Dd703_3019Imported
OrganismiDickeya paradisiaca (strain Ech703) (Dickeya dadantii (strain Ech703))Imported
Taxonomic identifieri579405 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaeDickeya
Proteomesi
  • UP000002734 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi579405.Dd703_3019

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 157MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105IRT Bacteria
COG3066 LUCA
HOGENOMiHOG000271839
KOiK03573
OMAiPPDLKRD
OrthoDBiPOG091H04RA

Family and domain databases

CDDicd00583 MutH_Sau3AI, 1 hit
Gene3Di3.40.600.10, 1 hit
HAMAPiMF_00759 MutH, 1 hit
InterProiView protein in InterPro
IPR004230 DNA_mismatch_repair_MutH
IPR011337 DNA_rep_MutH/RE_typeII
IPR037057 DNA_rep_MutH/RE_typeII_sf
IPR011335 Restrct_endonuc-II-like
PfamiView protein in Pfam
PF02976 MutH, 1 hit
SMARTiView protein in SMART
SM00927 MutH, 1 hit
SUPFAMiSSF52980 SSF52980, 1 hit
TIGRFAMsiTIGR02248 mutH_TIGR, 1 hit

Sequencei

Sequence statusi: Complete.

C6CC33-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIPMIHNDS PHSEQALAQR AQALAGYTLG ELARIAQLPI PPDLRRDKGW
60 70 80 90 100
TGILLERFLG ASAGSKPEQD FPDIGVELKT IPVDSEGKPL ETTFVCVAPL
110 120 130 140 150
TGNSGVTWEN SHVRHKLARV LWIPVEGARS IPLSQRHVGT PLLWSPSQKE
160 170 180 190 200
EEQLRQDWEE LMDLIVLGKV ESITARHGEV LQLRPKAANS RILTEAIGEH
210 220
GQPIMTLPRG FYLKKTFTAP LLARHFLL
Length:228
Mass (Da):25,345
Last modified:September 1, 2009 - v1
Checksum:i692FA5AD4C8269D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001654 Genomic DNA Translation: ACS86793.1

Genome annotation databases

EnsemblBacteriaiACS86793; ACS86793; Dd703_3019
KEGGidda:Dd703_3019

Similar proteinsi

Entry informationi

Entry nameiC6CC33_DICP7
AccessioniPrimary (citable) accession number: C6CC33
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 25, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health