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C6CA76

- C6CA76_DICDC

UniProt

C6CA76 - C6CA76_DICDC

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Protein

Alanine racemase

Gene

Dd703_0740

Organism
Dickeya dadantii (strain Ech703)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei129 – 1291SubstrateUniRule annotation
Active sitei254 – 2541Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei302 – 3021Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciDDAD579405:GHJU-753-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Dd703_0740Imported
OrganismiDickeya dadantii (strain Ech703)Imported
Taxonomic identifieri579405 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
ProteomesiUP000002734: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi579405.Dd703_0740.

Structurei

3D structure databases

ProteinModelPortaliC6CA76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031446.
KOiK01775.
OMAiWRDMARR.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6CA76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTATAVVDR SALRHNLQLI RQMAPQSRLI AIVKANAYGH GALEAARVFS
60 70 80 90 100
DADGYGVSRL SEALALRAGG ITKPILLLEG FFCADELPLL AEHQLETAVH
110 120 130 140 150
CVEQLAALEQ ATLPHPLKVW MKLDTGMHRL GVLPAHAEAF YARLSSCANV
160 170 180 190 200
VQPVNVMSHF CRADEPEFDT TRRQLDCFDA FTRGKPGAQS IAASGGILLW
210 220 230 240 250
PEAHRDQIRP GIILYGVSPL GHGDAGQWQL KPAMTLTSHL IAVREHHAGE
260 270 280 290 300
PVGYGSTWSS TRDTRLGVVA MGYGDGYPRG ARSGTPVWIN GREVPLVGRV
310 320 330 340 350
SMDMLTVDLG PDADDQVGNE VILWGGPLPV ENVAAHNDIS AYELITRLTA

RTRVEYIG
Length:358
Mass (Da):38,773
Last modified:September 1, 2009 - v1
Checksum:iC4DCCCFC110A377D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001654 Genomic DNA. Translation: ACS84551.1.
RefSeqiYP_002986373.1. NC_012880.1.

Genome annotation databases

EnsemblBacteriaiACS84551; ACS84551; Dd703_0740.
GeneIDi8088013.
KEGGidda:Dd703_0740.
PATRICi21788704. VBIDicDad95084_0803.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001654 Genomic DNA. Translation: ACS84551.1 .
RefSeqi YP_002986373.1. NC_012880.1.

3D structure databases

ProteinModelPortali C6CA76.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 579405.Dd703_0740.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACS84551 ; ACS84551 ; Dd703_0740 .
GeneIDi 8088013.
KEGGi dda:Dd703_0740.
PATRICi 21788704. VBIDicDad95084_0803.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031446.
KOi K01775.
OMAi WRDMARR.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci DDAD579405:GHJU-753-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ech703Imported.

Entry informationi

Entry nameiC6CA76_DICDC
AccessioniPrimary (citable) accession number: C6CA76
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3