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C6C8C4 (C6C8C4_DICDC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP-Rule MF_00223
EC=3.5.4.16 HAMAP-Rule MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP-Rule MF_00223
Gene names
Name:folE HAMAP-Rule MF_00223
Ordered Locus Names:Dd703_2306
OrganismDickeya dadantii (strain Ech703) [Complete proteome] [HAMAP] EMBL ACS86090.1
Taxonomic identifier579405 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Dickeya ›

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP-Rule MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP-Rule MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP-Rule MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP-Rule MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1101Zinc By similarity HAMAP-Rule MF_00223
Metal binding1131Zinc By similarity HAMAP-Rule MF_00223
Metal binding1811Zinc By similarity HAMAP-Rule MF_00223

Sequences

Sequence LengthMass (Da)Tools
C6C8C4 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: CE6AD821D518C52A

FASTA22224,824
        10         20         30         40         50         60 
MSSILSKEAA QVHEALLARG LETPLRGELQ DAETRKRLIA QHMTEIMNLL SLDLSDDSLA 

        70         80         90        100        110        120 
ETPHRIAKMY VDEIFSGLDY ANFPKITIIE NKMKVDEMVT VRDITLTSTC EHHFVTIDGK 

       130        140        150        160        170        180 
ATVAYIPKEG VIGLSKINRI VQFFSQRPQV QERLTQQILV ALQTLLGTNN VAVSIDAVHY 

       190        200        210        220 
CVKARGIRDA TSATTTTSLG GLFKSSQNTR QEFLRAVRHH SY

« Hide

References

[1]"Complete sequence of Dickeya dadantii Ech703."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Balakrishnan V., Glasner J., Perna N.T.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ech703.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001654 Genomic DNA. Translation: ACS86090.1.
RefSeqYP_002987912.1. NC_012880.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING579405.Dd703_2306.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS86090; ACS86090; Dd703_2306.
GeneID8086693.
KEGGdda:Dd703_2306.
PATRIC21792093. VBIDicDad95084_2468.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHOG000221222.
KOK01495.
OMAFYGKVHI.
ProtClustDBPRK09347.

Enzyme and pathway databases

BioCycDDAD579405:GHJU-2348-MONOMER.
UniPathwayUPA00848; UER00151.

Family and domain databases

HAMAPMF_00223. FolE.
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
PANTHERPTHR11109. PTHR11109. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. folE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6C8C4_DICDC
AccessionPrimary (citable) accession number: C6C8C4
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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