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C6C6V4 (C6C6V4_DICDC) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Dd703_2060 EMBL ACS85848.1
OrganismDickeya dadantii (strain Ech703) [Complete proteome] [HAMAP] EMBL ACS85848.1
Taxonomic identifier579405 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
C6C6V4 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: BA30E6F3C9068FA2

FASTA41745,960
        10         20         30         40         50         60 
MESKVVVPTE GQKITVDAQG KLIVPDNPII PFIEGDGIGI DVTPAMIKVV DAAVKKAYQG 

        70         80         90        100        110        120 
QRTISWMEIY TGEKSTQIYG KDVWLPDETL DFIREYRVAI KGPLTTPVGG GIRSLNVALR 

       130        140        150        160        170        180 
QQLDLYVCLR PVRYYEGTPS PVKQPELTDM VIFRENAEDI YAGIEWKAGS AEADKVIKFL 

       190        200        210        220        230        240 
QDEMGVKKIR FPQQCGIGVK PCSEEGTKRL VRAAIEYAIA NDRDSLTLVH KGNIMKFTEG 

       250        260        270        280        290        300 
AFKDWGYQLA REEFGGELID GGPWVSIKNP NSGKEIVVKD VIADAFLQQI LLRPAEYDVI 

       310        320        330        340        350        360 
ACMNLNGDYI SDALAAQVGG IGIAPGANIG DECALFEATH GTAPKYAGQD KVNPGSVILS 

       370        380        390        400        410 
AEMMLRHLRW YEAADLIVKG MEGAIKNKTV TYDFERLMDG AKLRKCSEFA QDIIDNM 

« Hide

References

[1]"Complete sequence of Dickeya dadantii Ech703."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Balakrishnan V., Glasner J., Perna N.T.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ech703 EMBL ACS85848.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001654 Genomic DNA. Translation: ACS85848.1.
RefSeqYP_002987670.1. NC_012880.1.

3D structure databases

ProteinModelPortalC6C6V4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING579405.Dd703_2060.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS85848; ACS85848; Dd703_2060.
GeneID8090657.
KEGGdda:Dd703_2060.
PATRIC21791545. VBIDicDad95084_2195.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000021113.
KOK00031.
OMACLRPIRY.
OrthoDBEOG6SNDTP.

Enzyme and pathway databases

BioCycDDAD579405:GHJU-2101-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6C6V4_DICDC
AccessionPrimary (citable) accession number: C6C6V4
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 14, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)