Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C6C6V4

- C6C6V4_DICDC

UniProt

C6C6V4 - C6C6V4_DICDC

Protein

Isocitrate dehydrogenase [NADP]

Gene

Dd703_2060

Organism
Dickeya dadantii (strain Ech703)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciDDAD579405:GHJU-2101-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Ordered Locus Names:Dd703_2060Imported
    OrganismiDickeya dadantii (strain Ech703)Imported
    Taxonomic identifieri579405 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
    ProteomesiUP000002734: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi579405.Dd703_2060.

    Structurei

    3D structure databases

    ProteinModelPortaliC6C6V4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6C6V4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESKVVVPTE GQKITVDAQG KLIVPDNPII PFIEGDGIGI DVTPAMIKVV    50
    DAAVKKAYQG QRTISWMEIY TGEKSTQIYG KDVWLPDETL DFIREYRVAI 100
    KGPLTTPVGG GIRSLNVALR QQLDLYVCLR PVRYYEGTPS PVKQPELTDM 150
    VIFRENAEDI YAGIEWKAGS AEADKVIKFL QDEMGVKKIR FPQQCGIGVK 200
    PCSEEGTKRL VRAAIEYAIA NDRDSLTLVH KGNIMKFTEG AFKDWGYQLA 250
    REEFGGELID GGPWVSIKNP NSGKEIVVKD VIADAFLQQI LLRPAEYDVI 300
    ACMNLNGDYI SDALAAQVGG IGIAPGANIG DECALFEATH GTAPKYAGQD 350
    KVNPGSVILS AEMMLRHLRW YEAADLIVKG MEGAIKNKTV TYDFERLMDG 400
    AKLRKCSEFA QDIIDNM 417
    Length:417
    Mass (Da):45,960
    Last modified:September 1, 2009 - v1
    Checksum:iBA30E6F3C9068FA2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001654 Genomic DNA. Translation: ACS85848.1.
    RefSeqiYP_002987670.1. NC_012880.1.

    Genome annotation databases

    EnsemblBacteriaiACS85848; ACS85848; Dd703_2060.
    GeneIDi8090657.
    KEGGidda:Dd703_2060.
    PATRICi21791545. VBIDicDad95084_2195.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001654 Genomic DNA. Translation: ACS85848.1 .
    RefSeqi YP_002987670.1. NC_012880.1.

    3D structure databases

    ProteinModelPortali C6C6V4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 579405.Dd703_2060.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACS85848 ; ACS85848 ; Dd703_2060 .
    GeneIDi 8090657.
    KEGGi dda:Dd703_2060.
    PATRICi 21791545. VBIDicDad95084_2195.

    Phylogenomic databases

    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci DDAD579405:GHJU-2101-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ech703Imported.

    Entry informationi

    Entry nameiC6C6V4_DICDC
    AccessioniPrimary (citable) accession number: C6C6V4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3