C6BTS9 (GLMM_DESAD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Desal_1797

Organism

Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763) [Complete proteome] [HAMAP]

Taxonomic identifier

526222 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › Desulfovibrio salexigens

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP-Rule MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 449	449	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_1000215485
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	C6BTS9 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 0A7A095BA35530D4	FASTA	449	49,380
	10 20 30 40 50 60 MSKRLFGTDG LRGQVNIFPM TAEVALRMGL AAGSYFRNGK QRHKVIIGKD TRLSGYVFES 70 80 90 100 110 120 ALTSGLCAMG MDVFQVGPMP TPAVSFLTRN MRADLGIVIS ASHNPFMDNG IKFFDSSGHK 130 140 150 160 170 180 LPDAVEDEIA DMVLSQDTQW DYPQAEKVGR AYKIEDARGR YIVYLKYSFP QDMTLNGVKL 190 200 210 220 230 240 VLDCANGAAY SLGHMFEELG AEVVRIGDKP NGLNINDKCG SLYPDILGQR VVEEHADLGL 250 260 270 280 290 300 ALDGDADRLI VVDEKGQVLD GDVIMAMCAA DLMERGKLNH NMLVATVMSN MALENFMKEN 310 320 330 340 350 360 GGSLLRTPVG DRYVVEAMRR EGAILGGEQS GHLIFKEFST TGDGLLAALQ LLRILCVKNR 370 380 390 400 410 420 PLSELSGLLE LYPQKLQNVH VKRKRPFEEV PAVQDALKQV EQELAGKGRV LLRYSGTESV 430 440 ARVMVEAEDS SKVELYTSEL AGVLEEHLR

References

[1]

"Complete sequence of Desulfovibrio salexigens DSM 2638." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. , Wall J.D., Arkin A.P., Dehal P., Chivian D., Giles B., Hazen T.C. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001649 Genomic DNA. Translation: ACS79859.1.
RefSeq	YP_002991398.1. NC_012881.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	526222.Desal_1797.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS79859; ACS79859; Desal_1797.
GeneID	8092898.
KEGG	dsa:Desal_1797.
PATRIC	21759091. VBIDesSal121003_1805.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
ProtClustDB	PRK14314.
Enzyme and pathway databases
BioCyc	DSAL526222:GHES-1825-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_DESAD

Accession

Primary (citable) accession number: C6BTS9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	September 1, 2009
Last modified:	May 29, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program