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Protein

Glutamate decarboxylase

Gene

Desal_3551

Organism
Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciDSAL526222:GHES-3656-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Desal_3551Imported
OrganismiDesulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763)Imported
Taxonomic identifieri526222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000002601 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi526222.Desal_3551.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C6BTB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHEKDKIRA ELLDDIYASS DLSLTMPKYK FPEEEHLPRD VYQVVHDELM
60 70 80 90 100
LDGNSRQNLA TFCSTWVDPE IHQLMDECVD KNMIDKDEYP QTAELENRCV
110 120 130 140 150
HMLADLWNSP DAANTLGCST TGSSEAAMLG GMAMKWRWRE KMKAQGKPVD
160 170 180 190 200
KPNMICGPVQ ICWHKFAKYW DVELREIPME KDRLIMSPEE VIKRCDENTI
210 220 230 240 250
GVVPTLGVTF TCDYEPVKEV CEALDKLQEE TGLDIPVHVD GASGGFIAPF
260 270 280 290 300
CDPDLEWDFR IKRVKSINTS GHKFGLSPLG VGWIIWRDRE DLPDDLIFWV
310 320 330 340 350
NYLGGNMPSF ALNFSRPGGQ IVAQYYNFLR LGKEGYRKIH QACYDTAAYI
360 370 380 390 400
ADEIDKLGVF DIVYNGRGGI PAVSWSLKEG SNPGFNCYDL SDKLRSRGWQ
410 420 430 440 450
VPAYSMPAHR EDLVLMRILV RHGVSRDLGS LLIEDMKRCL DYFKKNPVTN
460
SLGAEYGGYS HSSAK
Length:465
Mass (Da):52,847
Last modified:August 31, 2009 - v1
Checksum:i9621509F6E0259B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001649 Genomic DNA. Translation: ACS81597.1.
RefSeqiWP_015853413.1. NC_012881.1.
YP_002993136.1. NC_012881.1.

Genome annotation databases

EnsemblBacteriaiACS81597; ACS81597; Desal_3551.
KEGGidsa:Desal_3551.
PATRICi21762761. VBIDesSal121003_3566.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001649 Genomic DNA. Translation: ACS81597.1.
RefSeqiWP_015853413.1. NC_012881.1.
YP_002993136.1. NC_012881.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi526222.Desal_3551.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS81597; ACS81597; Desal_3551.
KEGGidsa:Desal_3551.
PATRICi21762761. VBIDesSal121003_3566.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciDSAL526222:GHES-3656-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763Imported.

Entry informationi

Entry nameiC6BTB6_DESAD
AccessioniPrimary (citable) accession number: C6BTB6
Entry historyi
Integrated into UniProtKB/TrEMBL: August 31, 2009
Last sequence update: August 31, 2009
Last modified: March 31, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.