Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

C6BRX2 (C6BRX2_DESAD) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2731Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3211Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C6BRX2 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 0975E2390630E382

FASTA38241,899
        10         20         30         40         50         60 
MNNPKTFAPI WAEVDLSAIS HNFSEVQRLV NKQSKIMAVV KADAYGHGLT KVADCLNKAG 

        70         80         90        100        110        120 
ADYFAVARLD EAVALRNHGI EKPILILGYT PPEAATELLK HKVIQTVFSS EYAKDLNEKL 

       130        140        150        160        170        180 
NQTNKTLKVH IKIDTGMGRL GLVDEFNDGA VLESISTINR LPNLETEGVY THFAASDEAD 

       190        200        210        220        230        240 
KTSALEQLKQ FKNILAGIER RGISIPLKHA ANSAAIIDLP ESYFDMVRPG IMLYGLYPSN 

       250        260        270        280        290        300 
GVHQQNAELR PAMQIKARIA QTKEVPAGFR ISYGHTYTTP NATKLATIPL GYADGYRRQL 

       310        320        330        340        350        360 
SSAGKVLVHG QHASIVGRVC MDQSVIDVGK IENVEAGDEV VIIGRQEQAE ISAERMACEL 

       370        380 
GTINYEIVST LMARVPRIFK DS 

« Hide

References

[1]"Complete sequence of Desulfovibrio salexigens DSM 2638."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I. expand/collapse author list , Wall J.D., Arkin A.P., Dehal P., Chivian D., Giles B., Hazen T.C.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001649 Genomic DNA. Translation: ACS81355.1.
RefSeqYP_002992894.1. NC_012881.1.

3D structure databases

ProteinModelPortalC6BRX2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING526222.Desal_3305.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS81355; ACS81355; Desal_3305.
GeneID8094315.
KEGGdsa:Desal_3305.
PATRIC21762239. VBIDesSal121003_3312.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAINNQLAP.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycDSAL526222:GHES-3401-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6BRX2_DESAD
AccessionPrimary (citable) accession number: C6BRX2
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)