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C6BI22 (C6BI22_RALP1) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methionyl-tRNA formyltransferase HAMAP-Rule MF_00182

EC=2.1.2.9 HAMAP-Rule MF_00182
Gene names
Name:fmt HAMAP-Rule MF_00182
Ordered Locus Names:Rpic12D_3354 EMBL ACS64618.1
OrganismRalstonia pickettii (strain 12D) [Complete proteome] [HAMAP] EMBL ACS64618.1
Taxonomic identifier428406 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeRalstonia

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP By similarity. HAMAP-Rule MF_00182 SAAS SAAS005794

Catalytic activity

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet). HAMAP-Rule MF_00182 SAAS SAAS005794

Sequence similarities

Belongs to the Fmt family. HAMAP-Rule MF_00182

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region122 – 1254Tetrahydrofolate (THF) binding By similarity HAMAP-Rule MF_00182

Sequences

Sequence LengthMass (Da)Tools
C6BI22 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 7E3E2F394B21FF93

FASTA32734,398
        10         20         30         40         50         60 
MTSTLRVAFA GTPEFAQIAL AAIHQAGFPV VAVLSQPDRP AGRGMQLQAS PVKQYAVTHG 

        70         80         90        100        110        120 
FAPILQPPSL RRAGKYPQEA AEVIDALAAQ RPDVMVVAAY GLILPQEVLD LPRFGCINIH 

       130        140        150        160        170        180 
ASLLPRWRGA APIHRAIEAG DAESGITLMQ MDAGLDTGDM IAMERVPIGL TDTTGTLHDT 

       190        200        210        220        230        240 
LAALGGRMVV EALAKLAQYG KLHATPQPAE GITYAEKIAK DEAALDWSRH AAALLRQVHA 

       250        260        270        280        290        300 
FNPFPGASAA LDGVAIKFWQ AEALADRPAE AEPGTVLAAN AEGVTIACGA GALRVTQLQK 

       310        320 
PGGKRLPARE FLQGLAIQPG QRFASRG 

« Hide

References

[1]"Complete sequence chromosome 1 of Ralstonia pickettii 12D."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Marsh T., Richardson P.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 12D EMBL ACS64618.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001644 Genomic DNA. Translation: ACS64618.1.
RefSeqYP_002983290.1. NC_012856.1.

3D structure databases

ProteinModelPortalC6BI22.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING428406.Rpic12D_3354.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS64618; ACS64618; Rpic12D_3354.
GeneID8021039.
KEGGrpf:Rpic12D_3354.
PATRIC20245789. VBIRalPic57998_3958.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0223.
HOGENOMHOG000261177.
KOK00604.
OMAKVWKAEV.
OrthoDBEOG6B09WV.
ProtClustDBPRK00005.

Enzyme and pathway databases

BioCycRPIC428406:GH9Y-3415-MONOMER.

Family and domain databases

Gene3D3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPMF_00182. Formyl_trans.
InterProIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERPTHR11138. PTHR11138. 1 hit.
PfamPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsTIGR00460. fmt. 1 hit.
PROSITEPS00373. GART. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6BI22_RALP1
AccessionPrimary (citable) accession number: C6BI22
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 16, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)