C6BE47 (C6BE47_RALP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3,4-dihydroxy-2-butanone 4-phosphate synthase EMBL ACS62007.1

Gene names

Ordered Locus Names:

Rpic12D_0706 EMBL ACS62007.1

Organism

Ralstonia pickettii (strain 12D) [Complete proteome] [HAMAP] EMBL ACS62007.1

Taxonomic identifier

428406 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia › Burkholderia pickettii

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate By similarity. SAAS SAAS017945
Catalytic activity	D-ribulose 5-phosphate = formate + L-3,4-dihydroxybutan-2-one 4-phosphate. SAAS SAAS017945
Cofactor	Binds 2 divalent metal cations per subunit. Magnesium or manganese By similarity. SAAS SAAS017945
Pathway	Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1. SAAS SAAS017945

Ontologies

Keywords
Biological process	Riboflavin biosynthesis SAAS SAAS017945
Ligand	Magnesium SAAS SAAS017945 Manganese SAAS SAAS017945 Metal-binding SAAS SAAS017945
Molecular function	Lyase SAAS SAAS017945
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	riboflavin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	3,4-dihydroxy-2-butanone-4-phosphate synthase activity Inferred from electronic annotation. Source: InterPro GTP cyclohydrolase II activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6BE47 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: ACA6D44F5D9643BC	FASTA	379	40,737
	10 20 30 40 50 60 MSIATVEEII AEIRAGRMVI LVDEEDRENE GDLILASDFV TPEAINFMVT HARGLVCLTL 70 80 90 100 110 120 TEEHCDQLDL PMMASRNGTQ FGTNFTVSIE AAEGVTTGIS AADRARTIQV AAAKNAKPSD 130 140 150 160 170 180 LVNPGHIFPL RAQKGGVLMR AGHTEAGCDL TAMAGLTPAA VICEILKDDG TMARLPDLVE 190 200 210 220 230 240 FAEKHGLKIG TIADMIQYRS RTESIVERVG ERTMETQFGT FHAVAFRDRA AGRAHLALVK 250 260 270 280 290 300 GTPTPDTETL VRVHEPLSVL DLLECQRTTH SWSVPAALRA IQAAPTGVVV LLNCGDSADR 310 320 330 340 350 360 LFTQFSALDA PHERPRTKPD PRIYGIGAQI LKDVGVGKMR VLASPLKLPS MVGYDLEVTA 370 YQSMADAPDV TSSASTATH

References

[1]

"Complete sequence chromosome 1 of Ralstonia pickettii 12D." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. , Ovchinnikova G., Marsh T., Richardson P. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 12D EMBL ACS62007.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001644 Genomic DNA. Translation: ACS62007.1.
RefSeq	YP_002980679.1. NC_012856.1.
3D structure databases
ProteinModelPortal	C6BE47.
SMR	C6BE47. Positions 3-203.
ModBase	Search...
Protein-protein interaction databases
STRING	428406.Rpic12D_0706.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS62007; ACS62007; Rpic12D_0706.
GeneID	8018333.
KEGG	rpf:Rpic12D_0706.
PATRIC	20240400. VBIRalPic57998_1317.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0108.
HOGENOM	HOG000115440.
KO	K14652.
OMA	DVHMALT.
ProtClustDB	PRK14019.
Enzyme and pathway databases
BioCyc	RPIC428406:GH9Y-1921-MONOMER.
UniPathway	UPA00275; UER00399.
Family and domain databases
Gene3D	3.90.870.10. 1 hit.
HAMAP	MF_00180. RibB.
InterPro	IPR017945. DHBP_synth_RibB-like_a/b_dom. IPR000422. DHBP_synthase_RibB. IPR000926. GTP_CycHdrlaseII_RibA. IPR016299. Riboflavin_synth_RibBA. [Graphical view]
Pfam	PF00926. DHBP_synthase. 1 hit. PF00925. GTP_cyclohydro2. 1 hit. [Graphical view]
PIRSF	PIRSF001259. RibA. 1 hit.
SUPFAM	SSF55821. DHBP_synth_RibB-like_a/b_dom. 1 hit.
TIGRFAMs	TIGR00506. ribB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6BE47_RALP1

Accession

Primary (citable) accession number: C6BE47

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)