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C6BC11 (C6BC11_RALP1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00817
EC=1.7.1.13 HAMAP MF_00817
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00817
NADPH-dependent nitrile oxidoreductase HAMAP MF_00817
PreQ(0) reductase HAMAP MF_00817
Gene names
Name:queF HAMAP MF_00817
Ordered Locus Names:Rpic12D_0339
OrganismRalstonia pickettii (strain 12D) [Complete proteome] [HAMAP]
Taxonomic identifier428406 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Ralstonia

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00817 SAAS SAAS016428

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00817 SAAS SAAS016428

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00817 SAAS SAAS016428

Subcellular location

Cytoplasm By similarity HAMAP MF_00817 SAAS SAAS016428.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily. HAMAP MF_00817

Sequences

Sequence LengthMass (Da)Tools
C6BC11 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 6B3A2C75E1C26776

FASTA27831,631
        10         20         30         40         50         60 
MSNQPEHSPL GKTSAYKTEY DPSLLFPIPR QGKRDEIGLA AGTPLPFFGV DLWNLYELSW 

        70         80         90        100        110        120 
LNLRGKPQVA LGTVIVPADS PNIVESKSFK LYLNSFNQTK VASHEALQQL IHHDLSEACG 

       130        140        150        160        170        180 
APVQVRIVTQ EEFARQKMGE LDGLLLDRLD IETDVYQPTP ELLHADEEES PVEETLVSHL 

       190        200        210        220        230        240 
LKSNCLVTGQ PDWGSVQIRY VGAPINQEAL LKYLISFREH NEFHEQCVER IFTDILRQCH 

       250        260        270 
PVKLAVYARY TRRGGLDINP FRTNYNTPWP DNLRNARQ

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References

[1]"Complete sequence chromosome 1 of Ralstonia pickettii 12D."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meincke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Marsh T., Richardson P.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 12D.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001644 Genomic DNA. Translation: ACS61645.1.
RefSeqYP_002980317.1. NC_012856.1.

3D structure databases

ProteinModelPortalC6BC11.
SMRC6BC11. Positions 16-278.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6BC11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8017963.
GenomeReviewsGene locus Rpic12D_0339 in contig CP001644_GR.
KEGGrpf:Rpic12D_0339.
PATRIC20239637. VBIRalPic57998_0938.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACVERIFC.
ProtClustDBPRK11792.

Family and domain databases

HAMAPMF_00817. QueF_type2.
[Tree]
InterProIPR016428. CN_OxRdtase_NADPH-dep_YqcD.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK06879.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF004750. Nitrile_oxidored_YqcD_prd. 1 hit.
TIGRFAMsTIGR03138. QueF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6BC11_RALP1
AccessionPrimary (citable) accession number: C6BC11
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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