C6B3N5 (C6B3N5_RHILS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP MF_00301
Short name=HK HAMAP MF_00301
Short name=HSK HAMAP MF_00301
EC=2.7.1.39 HAMAP MF_00301

Gene names

Name:	thrB HAMAP MF_00301
Ordered Locus Names:	Rleg_0652

Organism

Rhizobium leguminosarum bv. trifolii (strain WSM1325) [Complete proteome] [HAMAP]

Taxonomic identifier

395491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00301 SAAS SAAS002575
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00301 SAAS SAAS002575
Sequence similarities	Belongs to the pseudomonas-type thrB family. HAMAP MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP MF_00301 SAAS SAAS002575
Ligand	ATP-binding HAMAP MF_00301 SAAS SAAS002575 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00301 SAAS SAAS002575 EMBL ACS54956.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	threonine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6B3N5 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: CFD95022CF215F64	FASTA	327	36,514
	10 20 30 40 50 60 MKARPHLAVY TDIAEDDLKW FLTEYDAGTL LSYKGIAEGV ENSNFLLHTS RDPLILTLYE 70 80 90 100 110 120 KRVEKSDLPF FLGFMQHLSA RGLSCPLPLP RRDGALLGSL SGRPAALISF LEGMWLRKPE 130 140 150 160 170 180 AKHCREVGKA LAEMHVAGDG FELKRANALS IDGWRGLWEK SEARAGEVES GLQTEIRSEL 190 200 210 220 230 240 DFLSAAWPSG LPAGVIHADL FPDNVFFLGD QLSGLIDFYF ACNDLLAYDV SICLNAWCFE 250 260 270 280 290 300 KDGAYNITKG TAMLEGYQSV RPLSEAEIAA LPVLSRGSAL RFFLTRLYDW LTTPEGAMVT 310 320 KKDPLEYLRK LRFHRQIKSP AEYGLSL

References

[1]

"Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers." Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinnikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V. , Denton M., Yates R., Howieson J. Stand. Genomic Sci. 2:347-356(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM1325.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001622 Genomic DNA. Translation: ACS54956.1.
RefSeq	YP_002974495.1. NC_012850.1.
3D structure databases
ProteinModelPortal	C6B3N5.
SMR	C6B3N5. Positions 11-326.
ModBase	Search...
Protein-protein interaction databases
STRING	C6B3N5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8011830.
GenomeReviews	Gene locus Rleg_0652 in contig CP001622_GR.
KEGG	rlg:Rleg_0652.
PATRIC	23108680. VBIRhiLeg48398_1422.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ICLNAWC.
ProtClustDB	PRK05231.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2. [Tree]
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
KO	K02204.
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. ThrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6B3N5_RHILS

Accession

Primary (citable) accession number: C6B3N5

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)