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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

Rleg_3970

Organism
Rhizobium leguminosarum bv. trifolii (strain WSM1325)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

BioCyciRLEG395491:GHX2-4020-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported (EC:1.2.4.2Imported)
Gene namesi
Ordered Locus Names:Rleg_3970Imported
OrganismiRhizobium leguminosarum bv. trifolii (strain WSM1325)Imported
Taxonomic identifieri395491 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium
ProteomesiUP000002256 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi395491.Rleg_3970.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259586.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

C6AY62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARQEANEQF QITSFLDGAN AAYIEQLYAL YEEDPASVDD QWRSFFKALE
60 70 80 90 100
EDPSDVKRAA KGASWRKKNW PLQASGDLVS ALDGDWGIVE KVIETKVKAK
110 120 130 140 150
AEAQGKPADS TEVLQATRDS VRAIMMIRAY RMRGHLHAKL DPLGIAAPVD
160 170 180 190 200
DYHELSAENY GFTAADYDRK IFIDNVLGLE YATIREMIEI LERTYCSTLG
210 220 230 240 250
VEFMHISNPE EKAWIQERIE GPDKGVAFTP EGKKAILAKL VEAEGYEQFL
260 270 280 290 300
DVKFKGTKRF GLDGGESLIP ALEQILKRGG HLGLKEAVFG MAHRGRLNVL
310 320 330 340 350
SQVMGKPHRA IFHEFKGGSA APDEVEGSGD VKYHLGASSD REFDGNKIHV
360 370 380 390 400
SLTANPSHLE IVDPVVMGKA RAKQDMNATV WDGDIIPLSE RAKVLPLLIH
410 420 430 440 450
GDAAFAGQGV IAEILGLSGL RGHRVAGTMH VIINNQIGFT TNPAFSRSSP
460 470 480 490 500
YPSDVAKMIE APILHVNGDD PEAVVYGAKI ATEFRMKFHK PVVLDLFCYR
510 520 530 540 550
RYGHNEGDEP SFTQPKMYKV IRAHKTVLQL YAARLVAEGL LTDGEVEKMK
560 570 580 590 600
ADWRAHLEQE FEAGQHYKPN KADWLDGEWS GLRTADNADE QRRGKTAVPM
610 620 630 640 650
KTLKEIGRKL SEIPAGFNAH RTIQRFMENR ANMIATGEGI DWAMAEALSF
660 670 680 690 700
GALCVEGSKI RLSGQDCERG TFSQRHSVLY DQETEERYIP LANLSPTQGR
710 720 730 740 750
YEVINSMLSE EAVLGFEYGY SLARPNALTL WEAQFGDFAN GAQVVFDQFI
760 770 780 790 800
SSGERKWLRM SGLVCLLPHG YEGQGPEHSS ARLERFLQLC AEDNMQVANV
810 820 830 840 850
TTPANYFHIL RRQLKRDFRK PLVLMTPKSL LRHKRAVSTL AEMAGESAFH
860 870 880 890 900
RLLWDDAEVI KDGPIKLQKD NKIRRVVMCS GKVYYDLLEE REKRGIDDIY
910 920 930 940 950
LLRVEQLYPF PAKALINELS RFRNAEMVWC QEEPKNMGAW SFIDPFLEWV
960 970 980 990
LAHIDAKYQR VRYTGRPAAA SPATGLMSKH LSQLAAFLED ALGG
Length:994
Mass (Da):111,425
Last modified:September 1, 2009 - v1
Checksum:iEF832E00A7D89BF9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001622 Genomic DNA. Translation: ACS58211.1.
RefSeqiYP_002977750.1. NC_012850.1.

Genome annotation databases

EnsemblBacteriaiACS58211; ACS58211; Rleg_3970.
KEGGirlg:Rleg_3970.
PATRICi23115451. VBIRhiLeg48398_4763.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001622 Genomic DNA. Translation: ACS58211.1.
RefSeqiYP_002977750.1. NC_012850.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395491.Rleg_3970.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS58211; ACS58211; Rleg_3970.
KEGGirlg:Rleg_3970.
PATRICi23115451. VBIRhiLeg48398_4763.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259586.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciRLEG395491:GHX2-4020-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers."
    Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V.
    , Denton M., Yates R., Howieson J.
    Stand. Genomic Sci. 2:347-356(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WSM1325Imported.

Entry informationi

Entry nameiC6AY62_RHILS
AccessioniPrimary (citable) accession number: C6AY62
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 29, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.