C6AXY2 (C6AXY2_RHILS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate synthase HAMAP MF_00110
EC=4.2.3.4 HAMAP MF_00110

Gene names

Name:	aroB HAMAP MF_00110
Ordered Locus Names:	Rleg_3888

Organism

Rhizobium leguminosarum bv. trifolii (strain WSM1325) [Complete proteome] [HAMAP]

Taxonomic identifier

395491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. HAMAP MF_00110 NAD By similarity. HAMAP MF_00110
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity. HAMAP MF_00110
Subcellular location	Cytoplasm By similarity HAMAP MF_00110.
Sequence similarities	Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00110
Cellular component	Cytoplasm HAMAP MF_00110
Ligand	NAD HAMAP MF_00110
Molecular function	Lyase HAMAP MF_00110 EMBL ACS58131.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6AXY2 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 23E1B1DDCB46B26C	FASTA	376	39,967
	10 20 30 40 50 60 MNAITSASAI RTVHVPLGER AYDILIGPGL IARAGAEIAS RLKGRKAAVI TDENVAPLYL 70 80 90 100 110 120 KALVASLDEA GIASAEVVLP AGEKTKSFEH LITACDKVLE ARVERNDYVI ALGGGVIGDL 130 140 150 160 170 180 SGFAAGIVRR GVRFVQVPTS LLSQVDSSVG GKTGINSRHG KNLIGVFHQP DLVLADTDVL 190 200 210 220 230 240 NSLSAREFRA GYAEVAKYGL IDKPDFFAWL EANWKAVFTG GSARIEAIAA SCQAKADVVV 250 260 270 280 290 300 ADERENGQRA LLNLGHTFGH ALEAATAYDS SRLVHGEGVS IGMVLAHEFS ARMNLASPDD 310 320 330 340 350 360 ARRVERHLKE VGLPTRMSDI PGELPPAETL MDAIAQDKKV KSGKLTFILT RGIGQSFVAD 370 DVPASEVISF LREKHA

References

[1]

"Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers." Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinnikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V. , Denton M., Yates R., Howieson J. Stand. Genomic Sci. 2:347-356(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM1325.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001622 Genomic DNA. Translation: ACS58131.1.
RefSeq	YP_002977670.1. NC_012850.1.
3D structure databases
ProteinModelPortal	C6AXY2.
ModBase	Search...
Protein-protein interaction databases
STRING	C6AXY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8014708.
GenomeReviews	Gene locus Rleg_3888 in contig CP001622_GR.
KEGG	rlg:Rleg_3888.
PATRIC	23115289. VBIRhiLeg48398_4683.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	VMALEMS.
ProtClustDB	PRK00002.
Family and domain databases
HAMAP	MF_00110. DHQ_synthase. [Tree]
InterPro	IPR016037. DHQ_synth_AroB. [Graphical view]
KO	K01735.
PANTHER	PTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. AroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6AXY2_RHILS

Accession

Primary (citable) accession number: C6AXY2

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)