C6ASP4 (C6ASP4_RHILS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400
Ordered Locus Names:	Rleg_0998

Organism

Rhizobium leguminosarum bv. trifolii (strain WSM1325) [Complete proteome] [HAMAP]

Taxonomic identifier

395491 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Rhizobium

Protein attributes

Sequence length	137 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ACS55293.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	125	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	53	1	Zinc By similarity HAMAP MF_01400
	Metal binding	56	1	Zinc By similarity HAMAP MF_01400
	Metal binding	102	1	Zinc By similarity HAMAP MF_01400
	Metal binding	105	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	C6ASP4 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: EEB292FC1DC2590A	FASTA	137	15,354
	10 20 30 40 50 60 MSETATTAKI HKTDADWKEQ LTPEQYRITR QHGTERAFTG PYWDSFETGL YRCVGCNAPL 70 80 90 100 110 120 FRSDTKFDAG CGWPSYFEAV SPESVTEHRD TAFGMVRTEI RCGSCDAHLG HVFPDGPPPT 130 GLRYCINGHS MVFEPGK

References

[1]

"Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain WSM1325, an effective microsymbiont of annual Mediterranean clovers." Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R., Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinnikova G., Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V. , Denton M., Yates R., Howieson J. Stand. Genomic Sci. 2:347-356(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM1325.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001622 Genomic DNA. Translation: ACS55293.1.
RefSeq	YP_002974832.1. NC_012850.1.
3D structure databases
ProteinModelPortal	C6ASP4.
SMR	C6ASP4. Positions 11-136.
ModBase	Search...
Protein-protein interaction databases
STRING	C6ASP4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8012137.
GenomeReviews	Gene locus Rleg_0998 in contig CP001622_GR.
KEGG	rlg:Rleg_0998.
PATRIC	23109360. VBIRhiLeg48398_1760.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	APLFRSD.
ProtClustDB	PRK00222.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6ASP4_RHILS

Accession

Primary (citable) accession number: C6ASP4

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)