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C6AQ70

- C6AQ70_AGGAN

UniProt

C6AQ70 - C6AQ70_AGGAN

Protein

Ribonuclease PH

Gene

rph

Organism
Aggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
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    Functioni

    Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.UniRule annotationSAAS annotation

    Catalytic activityi

    tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. tRNA binding Source: InterPro
    2. tRNA nucleotidyltransferase activity Source: UniProtKB-EC
    3. tRNA-specific ribonuclease activity Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    NucleotidyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Biological processi

    tRNA processingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciAAPH634176:GHVL-1609-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease PHUniRule annotation (EC:2.7.7.56UniRule annotation)
    Short name:
    RNase PHUniRule annotation
    Alternative name(s):
    tRNA nucleotidyltransferaseUniRule annotation
    Gene namesi
    Name:rphUniRule annotation
    Ordered Locus Names:NT05HA_1649Imported
    OrganismiAggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)Imported
    Taxonomic identifieri634176 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
    ProteomesiUP000002733: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi634176.NT05HA_1649.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RNase PH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0689.
    HOGENOMiHOG000229516.
    KOiK00989.
    OMAiERTIQID.
    OrthoDBiEOG6CZQQP.

    Family and domain databases

    Gene3Di3.30.230.70. 1 hit.
    HAMAPiMF_00564. RNase_PH.
    InterProiIPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR027408. PNPase/RNase_PH_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR002381. RNase_PH_bac-type.
    IPR018336. RNase_PH_CS.
    [Graphical view]
    PfamiPF01138. RNase_PH. 1 hit.
    PF03725. RNase_PH_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    SSF55666. SSF55666. 1 hit.
    TIGRFAMsiTIGR01966. RNasePH. 1 hit.
    PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6AQ70-1 [UniParc]FASTAAdd to Basket

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    MRPNQRANNQ TRPIKITRHY TKHAEGSVLV EFGDTKVLCT ATVEEGVPRF    50
    LKGLGQGWVT AEYGMLPRST HSRMQREAAK GKQGGRTLEI QRLIARSLRA 100
    MVDLEALGER CITLDCDVIQ ADGGTRTASI TGACVALCDA LNGLVANGTL 150
    SKNPLKGLVA AISVGIVDGE AVCDLEYVED SAAETDMNVV MMEDGRMIEV 200
    QGTAEGEPFS HEELLTLLDL AKQGCDIIFQ TQRAALAD 238
    Length:238
    Mass (Da):25,661
    Last modified:September 1, 2009 - v1
    Checksum:i2E380F99D4585AA8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001607 Genomic DNA. Translation: ACS97982.1.
    RefSeqiYP_003008069.1. NC_012913.1.

    Genome annotation databases

    EnsemblBacteriaiACS97982; ACS97982; NT05HA_1649.
    GeneIDi8123044.
    KEGGiaap:NT05HA_1649.
    PATRICi31918312. VBIAggAph86045_1544.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001607 Genomic DNA. Translation: ACS97982.1 .
    RefSeqi YP_003008069.1. NC_012913.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 634176.NT05HA_1649.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACS97982 ; ACS97982 ; NT05HA_1649 .
    GeneIDi 8123044.
    KEGGi aap:NT05HA_1649.
    PATRICi 31918312. VBIAggAph86045_1544.

    Phylogenomic databases

    eggNOGi COG0689.
    HOGENOMi HOG000229516.
    KOi K00989.
    OMAi ERTIQID.
    OrthoDBi EOG6CZQQP.

    Enzyme and pathway databases

    BioCyci AAPH634176:GHVL-1609-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.70. 1 hit.
    HAMAPi MF_00564. RNase_PH.
    InterProi IPR001247. ExoRNase_PH_dom1.
    IPR015847. ExoRNase_PH_dom2.
    IPR027408. PNPase/RNase_PH_dom.
    IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR002381. RNase_PH_bac-type.
    IPR018336. RNase_PH_CS.
    [Graphical view ]
    Pfami PF01138. RNase_PH. 1 hit.
    PF03725. RNase_PH_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    SSF55666. SSF55666. 1 hit.
    TIGRFAMsi TIGR01966. RNasePH. 1 hit.
    PROSITEi PS01277. RIBONUCLEASE_PH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700."
      Di Bonaventura M.P., DeSalle R., Pop M., Nagarajan N., Figurski D.H., Fine D.H., Kaplan J.B., Planet P.J.
      J. Bacteriol. 191:4693-4694(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NJ8700Imported.

    Entry informationi

    Entry nameiC6AQ70_AGGAN
    AccessioniPrimary (citable) accession number: C6AQ70
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3