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Protein

Ribonuclease PH

Gene

rph

Organism
Aggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.SAAS annotation

Catalytic activityi

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseSAAS annotationImported, Transferase

Keywords - Biological processi

tRNA processingSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease PHSAAS annotation (EC:2.7.7.56SAAS annotation)
Gene namesi
Name:rphImported
ORF Names:NJ8700_07750Imported
OrganismiAggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)Imported
Taxonomic identifieri634176 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 140130RNase_PHInterPro annotationAdd
BLAST
Domaini157 – 22468RNase_PH_CInterPro annotationAdd
BLAST

Phylogenomic databases

KOiK00989.

Family and domain databases

Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamiPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6AQ70-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPNQRANNQ TRPIKITRHY TKHAEGSVLV EFGDTKVLCT ATVEEGVPRF
60 70 80 90 100
LKGLGQGWVT AEYGMLPRST HSRMQREAAK GKQGGRTLEI QRLIARSLRA
110 120 130 140 150
MVDLEALGER CITLDCDVIQ ADGGTRTASI TGACVALCDA LNGLVANGTL
160 170 180 190 200
SKNPLKGLVA AISVGIVDGE AVCDLEYVED SAAETDMNVV MMEDGRMIEV
210 220 230
QGTAEGEPFS HEELLTLLDL AKQGCDIIFQ TQRAALAD
Length:238
Mass (Da):25,661
Last modified:September 1, 2009 - v1
Checksum:i2E380F99D4585AA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009230 Genomic DNA. Translation: AKS65293.1.
RefSeqiWP_005702222.1. NZ_CP009230.1.

Genome annotation databases

EnsemblBacteriaiACS97982; ACS97982; NT05HA_1649.
KEGGiaap:NT05HA_1649.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009230 Genomic DNA. Translation: AKS65293.1.
RefSeqiWP_005702222.1. NZ_CP009230.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS97982; ACS97982; NT05HA_1649.
KEGGiaap:NT05HA_1649.

Phylogenomic databases

KOiK00989.

Family and domain databases

Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamiPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "DNA barcoding of Bradysia (Diptera: Sciaridae) for detection of the immature stages on agricultural crops."
    Shin S., Jung S., Heller K., Menzel F., Hong T.-K., Lee H., Lee S.
    Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NJ8700Imported.

Entry informationi

Entry nameiC6AQ70_AGGAN
AccessioniPrimary (citable) accession number: C6AQ70
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 17, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.