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C6AQ70

- C6AQ70_AGGAN

UniProt

C6AQ70 - C6AQ70_AGGAN

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Protein

Ribonuclease PH

Gene

rph

Organism
Aggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.UniRule annotationSAAS annotation

Catalytic activityi

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. tRNA binding Source: InterPro
  2. tRNA nucleotidyltransferase activity Source: UniProtKB-EC
  3. tRNA-specific ribonuclease activity Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAAPH634176:GHVL-1609-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease PHUniRule annotation (EC:2.7.7.56UniRule annotation)
Short name:
RNase PHUniRule annotation
Alternative name(s):
tRNA nucleotidyltransferaseUniRule annotation
Gene namesi
Name:rphUniRule annotation
Ordered Locus Names:NT05HA_1649Imported
OrganismiAggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)Imported
Taxonomic identifieri634176 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
ProteomesiUP000002733: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi634176.NT05HA_1649.

Family & Domainsi

Sequence similaritiesi

Belongs to the RNase PH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0689.
HOGENOMiHOG000229516.
KOiK00989.
OMAiERTIQID.
OrthoDBiEOG6CZQQP.

Family and domain databases

Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamiPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6AQ70-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPNQRANNQ TRPIKITRHY TKHAEGSVLV EFGDTKVLCT ATVEEGVPRF
60 70 80 90 100
LKGLGQGWVT AEYGMLPRST HSRMQREAAK GKQGGRTLEI QRLIARSLRA
110 120 130 140 150
MVDLEALGER CITLDCDVIQ ADGGTRTASI TGACVALCDA LNGLVANGTL
160 170 180 190 200
SKNPLKGLVA AISVGIVDGE AVCDLEYVED SAAETDMNVV MMEDGRMIEV
210 220 230
QGTAEGEPFS HEELLTLLDL AKQGCDIIFQ TQRAALAD
Length:238
Mass (Da):25,661
Last modified:September 1, 2009 - v1
Checksum:i2E380F99D4585AA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001607 Genomic DNA. Translation: ACS97982.1.
RefSeqiWP_005702222.1. NC_012913.1.
YP_003008069.1. NC_012913.1.

Genome annotation databases

EnsemblBacteriaiACS97982; ACS97982; NT05HA_1649.
GeneIDi8123044.
KEGGiaap:NT05HA_1649.
PATRICi31918312. VBIAggAph86045_1544.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001607 Genomic DNA. Translation: ACS97982.1 .
RefSeqi WP_005702222.1. NC_012913.1.
YP_003008069.1. NC_012913.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 634176.NT05HA_1649.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACS97982 ; ACS97982 ; NT05HA_1649 .
GeneIDi 8123044.
KEGGi aap:NT05HA_1649.
PATRICi 31918312. VBIAggAph86045_1544.

Phylogenomic databases

eggNOGi COG0689.
HOGENOMi HOG000229516.
KOi K00989.
OMAi ERTIQID.
OrthoDBi EOG6CZQQP.

Enzyme and pathway databases

BioCyci AAPH634176:GHVL-1609-MONOMER.

Family and domain databases

Gene3Di 3.30.230.70. 1 hit.
HAMAPi MF_00564. RNase_PH.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view ]
Pfami PF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsi TIGR01966. RNasePH. 1 hit.
PROSITEi PS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700."
    Di Bonaventura M.P., DeSalle R., Pop M., Nagarajan N., Figurski D.H., Fine D.H., Kaplan J.B., Planet P.J.
    J. Bacteriol. 191:4693-4694(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NJ8700Imported.

Entry informationi

Entry nameiC6AQ70_AGGAN
AccessioniPrimary (citable) accession number: C6AQ70
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3