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C6ANE3 (C6ANE3_AGGAN) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B HAMAP-Rule MF_01080
EC=5.4.99.25 HAMAP-Rule MF_01080
Alternative name(s):
tRNA pseudouridine(55) synthase HAMAP-Rule MF_01080
tRNA pseudouridylate synthase HAMAP-Rule MF_01080
tRNA-uridine isomerase HAMAP-Rule MF_01080
Gene names
Name:truB HAMAP-Rule MF_01080
Ordered Locus Names:NT05HA_0980
OrganismAggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus) [Complete proteome] [HAMAP] EMBL ACS97355.1
Taxonomic identifier634176 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Aggregatibacter ›

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080 SAAS SAAS002501

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080 SAAS SAAS002501

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. HAMAP-Rule MF_01080

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site481Nucleophile By similarity HAMAP-Rule MF_01080

Sequences

Sequence LengthMass (Da)Tools
C6ANE3 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: CEDA55C95C93A923

FASTA30634,171
        10         20         30         40         50         60 
MSKPRKRGRD IHGVFLLDKP QGMSSNDIMQ KVKRIFQANK AGHTGALDPL ATGMLPICLG 

        70         80         90        100        110        120 
EATKFSQFLL DADKRYLVTA KLGERTDTSD AEGQIVETRE VKVKTPEILT ALEQFRGDIL 

       130        140        150        160        170        180 
QVPTMFSALK HNGKPLYEYA RQGITVEREA RPITIFELNF IEYNAPYLTL EVHCSKGTYI 

       190        200        210        220        230        240 
RTLVDDLGEV LGCGAHVTML RRTAVADYPT EKMLDWNALQ SLAAQQDLAL LDALLLPMDT 

       250        260        270        280        290        300 
AVAKLPTLTL DESQAQGIGF GQRVKFNNPN SLQGQVRLFS HENRFLGVAV IDENNVIRPQ 


RLVVYE

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References

[1]"Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700."
Di Bonaventura M.P., DeSalle R., Pop M., Nagarajan N., Figurski D.H., Fine D.H., Kaplan J.B., Planet P.J.
J. Bacteriol. 191:4693-4694(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NJ8700.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001607 Genomic DNA. Translation: ACS97355.1.
RefSeqYP_003007442.1. NC_012913.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING634176.NT05HA_0980.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS97355; ACS97355; NT05HA_0980.
GeneID8122946.
KEGGaap:NT05HA_0980.
PATRIC31917028. VBIAggAph86045_0925.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231223.
KOK03177.
OMALGCGAYV.
ProtClustDBPRK05033.

Enzyme and pathway databases

BioCycAAPH634176:GHVL-951-MONOMER.

Family and domain databases

Gene3D2.30.130.10. 1 hit.
HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6ANE3_AGGAN
AccessionPrimary (citable) accession number: C6ANE3
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 29, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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