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C6ANE3

- C6ANE3_AGGAN

UniProt

C6ANE3 - C6ANE3_AGGAN

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Protein
tRNA pseudouridine synthase B
Gene
truB, NT05HA_0980
Organism
Aggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity.UniRule annotationSAAS annotations

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei48 – 481Nucleophile By similarityUniRule annotation

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. pseudouridine synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAAPH634176:GHVL-951-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:NT05HA_0980Imported
OrganismiAggregatibacter aphrophilus (strain NJ8700) (Haemophilus aphrophilus)Imported
Taxonomic identifieri634176 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeAggregatibacter
ProteomesiUP000002733: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi634176.NT05HA_0980.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231223.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

C6ANE3-1 [UniParc]FASTAAdd to Basket

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MSKPRKRGRD IHGVFLLDKP QGMSSNDIMQ KVKRIFQANK AGHTGALDPL    50
ATGMLPICLG EATKFSQFLL DADKRYLVTA KLGERTDTSD AEGQIVETRE 100
VKVKTPEILT ALEQFRGDIL QVPTMFSALK HNGKPLYEYA RQGITVEREA 150
RPITIFELNF IEYNAPYLTL EVHCSKGTYI RTLVDDLGEV LGCGAHVTML 200
RRTAVADYPT EKMLDWNALQ SLAAQQDLAL LDALLLPMDT AVAKLPTLTL 250
DESQAQGIGF GQRVKFNNPN SLQGQVRLFS HENRFLGVAV IDENNVIRPQ 300
RLVVYE 306
Length:306
Mass (Da):34,171
Last modified:September 1, 2009 - v1
Checksum:iCEDA55C95C93A923
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001607 Genomic DNA. Translation: ACS97355.1.
RefSeqiWP_005700692.1. NC_012913.1.
YP_003007442.1. NC_012913.1.

Genome annotation databases

EnsemblBacteriaiACS97355; ACS97355; NT05HA_0980.
GeneIDi8122946.
KEGGiaap:NT05HA_0980.
PATRICi31917028. VBIAggAph86045_0925.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001607 Genomic DNA. Translation: ACS97355.1 .
RefSeqi WP_005700692.1. NC_012913.1.
YP_003007442.1. NC_012913.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 634176.NT05HA_0980.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACS97355 ; ACS97355 ; NT05HA_0980 .
GeneIDi 8122946.
KEGGi aap:NT05HA_0980.
PATRICi 31917028. VBIAggAph86045_0925.

Phylogenomic databases

eggNOGi COG0130.
HOGENOMi HOG000231223.
KOi K03177.
OMAi YELQFIR.
OrthoDBi EOG6358D3.

Enzyme and pathway databases

BioCyci AAPH634176:GHVL-951-MONOMER.

Family and domain databases

Gene3Di 2.30.130.10. 1 hit.
HAMAPi MF_01080. TruB_bact.
InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Aggregatibacter (Haemophilus) aphrophilus NJ8700."
    Di Bonaventura M.P., DeSalle R., Pop M., Nagarajan N., Figurski D.H., Fine D.H., Kaplan J.B., Planet P.J.
    J. Bacteriol. 191:4693-4694(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NJ8700Imported.

Entry informationi

Entry nameiC6ANE3_AGGAN
AccessioniPrimary (citable) accession number: C6ANE3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 3, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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