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C6AHR9

- C6AHR9_BIFAS

UniProt

C6AHR9 - C6AHR9_BIFAS

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Protein

Alanine racemase

Gene

Balat_0584

Organism
Bifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei66 – 661Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei168 – 1681SubstrateUniRule annotation
Active sitei306 – 3061Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei370 – 3701Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBANI555970:GJ22-584-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Balat_0584Imported
OrganismiBifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314)Imported
Taxonomic identifieri555970 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000009076: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei66 – 661N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi555970.Balat_0584.

Structurei

3D structure databases

ProteinModelPortaliC6AHR9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6AHR9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVCMSVSALE EWQFSSEQGE RNYNQALREY PAQVIVDLAA LRDNMRHLVD
60 70 80 90 100
ITNREGGPTE VMGVVKADAY GHGLVPSALA ALAGGATWLG VAQAREALAL
110 120 130 140 150
RNAGIGVDRA RVLTWVNNPL HAPYDDLIAA DVDLSVATLT AIQKIAEAAR
160 170 180 190 200
AVGKPARVHI KVDTGFGRNG FTLAQIDSAI DLLLPLVDEG VFEIVGQWSH
210 220 230 240 250
LAVADAPAVG EFVEKTDEQI RVFEEFTSRL HARGIEPRIR HLANTAATLS
260 270 280 290 300
RPEIHYDLVR PGVALYGYEA DPAMGTPSKY ELRPAMTLQA QLSSVKNVGA
310 320 330 340 350
GEGLSYGRVY VTDEPTSAAI VPVGYADGIH RSASGFNEAG SKHVNKPGAP
360 370 380 390 400
VRVMTRDGAR IFHVSGRVCM DQFILDLHGD AENMGVHIGD TVELFGPGRG
410 420 430 440 450
EDYLEPTADD WARAADTISY EIFTCLRNRV PRLYANAFEV LDETDLGKLD

QSTLL
Length:455
Mass (Da):49,253
Last modified:September 1, 2009 - v1
Checksum:i7C040E0385AB7865
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001606 Genomic DNA. Translation: ACS47526.1.
RefSeqiYP_002969588.1. NC_012815.1.

Genome annotation databases

EnsemblBacteriaiACS47526; ACS47526; Balat_0584.
GeneIDi8010206.
KEGGiblt:Balat_0584.
PATRICi21110740. VBIBifAni93544_0592.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001606 Genomic DNA. Translation: ACS47526.1 .
RefSeqi YP_002969588.1. NC_012815.1.

3D structure databases

ProteinModelPortali C6AHR9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 555970.Balat_0584.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACS47526 ; ACS47526 ; Balat_0584 .
GeneIDi 8010206.
KEGGi blt:Balat_0584.
PATRICi 21110740. VBIBifAni93544_0592.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BANI555970:GJ22-584-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10140 / JCM 10602 / LMG 18314Imported.

Entry informationi

Entry nameiC6AHR9_BIFAS
AccessioniPrimary (citable) accession number: C6AHR9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3