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Protein

Aldehyde-alcohol dehydrogenase

Gene

Balat_0378

Organism
Bifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. acetaldehyde dehydrogenase (acetylating) activity Source: InterPro
  2. alcohol dehydrogenase (NAD) activity Source: InterPro
  3. metal ion binding Source: InterPro

GO - Biological processi

  1. alcohol metabolic process Source: InterPro
  2. carbon utilization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Enzyme and pathway databases

BioCyciBANI555970:GJ22-378-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde-alcohol dehydrogenaseUniRule annotation
Gene namesi
Ordered Locus Names:Balat_0378Imported
OrganismiBifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314)Imported
Taxonomic identifieri555970 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000009076: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi555970.Balat_0378.

Structurei

3D structure databases

ProteinModelPortaliC6AH71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.UniRule annotation
In the N-terminal section; belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000025256.
KOiK04072.
OMAiWHKLPSS.
OrthoDBiEOG6TFCQS.

Family and domain databases

Gene3Di3.40.309.10. 2 hits.
3.40.605.10. 1 hit.
InterProiIPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR012079. Bifunc_Ald-ADH.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
PF00465. Fe-ADH. 1 hit.
[Graphical view]
PIRSFiPIRSF000111. ALDH_ADH. 1 hit.
SUPFAMiSSF53720. SSF53720. 2 hits.
PROSITEiPS00060. ADH_IRON_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6AH71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKNSAETA TKAAKLAVNV EDKKAAAQAE VDALVRKAQK ALAEFEKLDQ
60 70 80 90 100
QAVDRIVAKA SVAALNKHLV LAKLAVDETG RGLVEDKATK NIFACEHVTN
110 120 130 140 150
YMAGQKTVGI IREDDVLGID EVAEPVGVVA GVTPVTNPTS TAIFKSLIAL
160 170 180 190 200
KTRCPIVFGF HPGAQKSSVE AARIVRDAAI EAGAPENCVQ WIEHPSIEAT
210 220 230 240 250
GALMQHPGVA TILATGGPGM VKAAYSSGKP ALGVGAGNAP AYVDNNVDVQ
260 270 280 290 300
RVANDLILSK HFDYGMICAT EQAIIAHKDI YAPLVKELKR RKAYFVNDEE
310 320 330 340 350
KAKLEKYMFG CTAFSGETPK LNSVVPGKSP QYIAHEAGFE IPEDATILAA
360 370 380 390 400
ECSEVGENEP LTMEKLAPVH AVLKFSDKEQ GFEMCEEMLK HGAGHTAAIH
410 420 430 440 450
TNNDDLVREY GLRMHACRII WNQPSSLGGI GDIYNSIAPS LTLGCGSYGG
460 470 480 490 500
NSVSGNVQAI NLLNIKRIAR RNNNMQWFKI PAKTYFEPNA IKYLRDMYGI
510 520 530 540 550
ERAVIVCDKV MEQLGIVDKV IDQLRARSNR VTFRIVDYVE PEPSVETVER
560 570 580 590 600
GAAMMRDEFE PDTIIAVGGG SPMDAAKIMW LLYEHPEIAF SDVREKFFDI
610 620 630 640 650
RKRAFKIPPL GTKAKLVCIP TSSGTGSEVT PFAVITDHKT GYKYPITDYA
660 670 680 690 700
LTPSVAIVDP VLARTQPRRL ASDAGFDALT HSMEAYVSVY ANDFTDGMAL
710 720 730 740 750
HACKLIWDNL AESVNSEPGE TKKKAQEKMH NAATMAGMAF GSAFLGMCHA
760 770 780 790 800
MAHTIGALCH IAHGRTNSIL LPYVIRYNGQ VPEEPTSWPK YSKYIAPERY
810 820 830 840 850
QELASLLGVD PGKTPAEGVE NLAKAVEDYR DNKLGMNKSF KDCGVDEDYF
860 870 880 890 900
WSILEQIGMR AYEDQCAPAN PRIPQIQDMM DIAIAAYYGV SQAEGHAMRV
910
EREGVGATEE ASERV
Length:915
Mass (Da):99,641
Last modified:September 1, 2009 - v1
Checksum:i383147AA7747EFA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001606 Genomic DNA. Translation: ACS47328.1.
RefSeqiYP_002969390.1. NC_012815.1.

Genome annotation databases

EnsemblBacteriaiACS47328; ACS47328; Balat_0378.
GeneIDi8010000.
KEGGiblt:Balat_0378.
PATRICi21110308. VBIBifAni93544_0384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001606 Genomic DNA. Translation: ACS47328.1.
RefSeqiYP_002969390.1. NC_012815.1.

3D structure databases

ProteinModelPortaliC6AH71.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi555970.Balat_0378.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS47328; ACS47328; Balat_0378.
GeneIDi8010000.
KEGGiblt:Balat_0378.
PATRICi21110308. VBIBifAni93544_0384.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000025256.
KOiK04072.
OMAiWHKLPSS.
OrthoDBiEOG6TFCQS.

Enzyme and pathway databases

BioCyciBANI555970:GJ22-378-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 2 hits.
3.40.605.10. 1 hit.
InterProiIPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR012079. Bifunc_Ald-ADH.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
PF00465. Fe-ADH. 1 hit.
[Graphical view]
PIRSFiPIRSF000111. ALDH_ADH. 1 hit.
SUPFAMiSSF53720. SSF53720. 2 hits.
PROSITEiPS00060. ADH_IRON_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 10140 / JCM 10602 / LMG 18314Imported.

Entry informationi

Entry nameiC6AH71_BIFAS
AccessioniPrimary (citable) accession number: C6AH71
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: January 7, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.