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C6AGU9 (C6AGU9_BIFAS) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length378 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain149 – 374226ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding189 – 24759ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3281Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3411Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3411Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3431Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C6AGU9 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 23FCACC423C71CB1

FASTA37840,445
        10         20         30         40         50         60 
MAKTRVAVLY GGKADEHSIS CISAASFMRA LDPELFEAVP IGITKTGTWF VDGQDPLGWN 

        70         80         90        100        110        120 
LAEGLPEAVE TPDSREVVLT IGDGGDGFHA RNADGSLDSL GHIDVVLPAL HGPFGEDGTI 

       130        140        150        160        170        180 
QGLFEMMGVP YVGCGVLASA ACMDKHYTKV LLRAAGIPVA PGITLDTRHY DASDEFATDG 

       190        200        210        220        230        240 
EEFLRQVNEA GLQYPLFVKP SRAGSSFGVT KVEQIGDAAA LAAAVFEASR HDWRVLVEQG 

       250        260        270        280        290        300 
IDAREIECAV VRIHPTDPTR AALPGEVVLD RRSEGDDQFY DFDSKYMDSQ ASHTEIPAKI 

       310        320        330        340        350        360 
GDDLIARVRE TAVRAFDAVD GMGLSRVDTF VTADGDVLVN EINTLPGCTS ISMFPQAWEA 

       370 
MGIPFRTVVT DLIEGALA 

« Hide

References

[1]"Comparison of the complete genome sequences of Bifidobacterium animalis subsp. lactis DSM 10140 and Bl-04."
Barrangou R., Briczinski E.P., Traeger L.L., Loquasto J.R., Richards M., Horvath P., Coute-Monvoisin A.C., Leyer G., Rendulic S., Steele J.L., Broadbent J.R., Oberg T., Dudley E.G., Schuster S., Romero D.A., Roberts R.F.
J. Bacteriol. 191:4144-4151(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 10140 / JCM 10602 / LMG 18314.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001606 Genomic DNA. Translation: ACS47206.1.
RefSeqYP_002969268.1. NC_012815.1.

3D structure databases

ProteinModelPortalC6AGU9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING555970.Balat_0248.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS47206; ACS47206; Balat_0248.
GeneID8009870.
KEGGblt:Balat_0248.
PATRIC21110026. VBIBifAni93544_0251.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011593.
KOK01921.
OMAQIDVIFP.
OrthoDBEOG64BQ73.

Enzyme and pathway databases

BioCycBANI555970:GJ22-248-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6AGU9_BIFAS
AccessionPrimary (citable) accession number: C6AGU9
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)