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C6AB48 (C6AB48_BARGA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase HAMAP-Rule MF_00177
EC=6.1.1.6 HAMAP-Rule MF_00177
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00177
Gene names
Name:lysS HAMAP-Rule MF_00177 EMBL ACS50415.1
Ordered Locus Names:Bgr_00230 EMBL ACS50415.1
OrganismBartonella grahamii (strain as4aup) [Complete proteome] [HAMAP] EMBL ACS50415.1
Taxonomic identifier634504 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella ›

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP-Rule MF_00177

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00177.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00177 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif54 – 629"HIGH" region By similarity HAMAP-Rule MF_00177
Motif304 – 3085"KMSKS" region By similarity HAMAP-Rule MF_00177

Sites

Binding site3071ATP By similarity HAMAP-Rule MF_00177

Sequences

Sequence LengthMass (Da)Tools
C6AB48 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: DC3F6BCAFB72927E

FASTA55362,758
        10         20         30         40         50         60 
MMRDQCDTLN LTPELKDAAS QSRTWPFEEA RKIIKRYEKT GYPDSVIFET GYGPSGLPHI 

        70         80         90        100        110        120 
GTFGEVARTT MVRHAFHILT ENKVKTKLLC FSDDMDGLRK VPENVPDRER MEHYLGQPLS 

       130        140        150        160        170        180 
RVPDPFGDDY PSFGAANNAR LRAFLDRFGF DYEFASATDY YHSGRFDETL LKILACYDKV 

       190        200        210        220        230        240 
MAIILPTLGA ERQATYSLFL PISPFSGKVL QVPMIERNVE KGTVTYIEPE TGETIETEVT 

       250        260        270        280        290        300 
GGKVKCQWKV DWAMRWTALG IDYEMAGKDL IDSTNLSSKI CKVLGGKSPE GFNYELFLDE 

       310        320        330        340        350        360 
KGQKISKSKG NGLTIDEWLT YAPTESLGLY MFSKPKTAKR LYFDVIPKAV DEYYAHLSAY 

       370        380        390        400        410        420 
GRQEWKERLN NPVWHIHNGC PPQVDLPVSF AMLLNLVSAS NAENAEVLWG FISRYAKGAN 

       430        440        450        460        470        480 
AQTYPELDQL VKFAIRYFDV FVKPNKKFRL PDESERTTLA QIDEKLANLP ETVDGNMLQN 

       490        500        510        520        530        540 
MLLDVARLTE RYQDHSKKSP EGGPGVSNVF FQMLYEVLLG QERGPRWGSF IALYGINEMR 

       550 
ALIAEALARP TEE

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References

[1]"Run-off replication of host-adaptability genes is associated with gene transfer agents in the genome of mouse-infecting Bartonella grahamii."
Berglund E.C., Frank A.C., Calteau A., Vinnere Pettersson O., Granberg F., Eriksson A.-S., Naslund K., Holmberg M., Lindroos H., Andersson S.G.E.
PLoS Genet. 5:e1000546-e1000546(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: as4aup.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001562 Genomic DNA. Translation: ACS50415.1.
RefSeqYP_002971092.1. NC_012846.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING634504.Bgr_00230.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS50415; ACS50415; Bgr_00230.
GeneID7996999.
KEGGbgr:Bgr_00230.
PATRIC20539126. VBIBarGra67450_0026.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1384.
HOGENOMHOG000140447.
KOK04566.
OMATMVRHAF.
ProtClustDBPRK00750.

Enzyme and pathway databases

BioCycBGRA634504:GJI6-23-MONOMER.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00177. Lys_tRNA_synth_class1.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR002904. Lys-tRNA-ligase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01921. tRNA-synt_1f. 1 hit.
[Graphical view]
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00467. lysS_arch. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6AB48_BARGA
AccessionPrimary (citable) accession number: C6AB48
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info