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C6A761

- C6A761_BIFLB

UniProt

C6A761 - C6A761_BIFLB

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Protein
Alanine racemase
Gene
Balac_0584
Organism
Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei66 – 661Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei168 – 1681Substrate By similarityUniRule annotation
Active sitei306 – 3061Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei370 – 3701Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBANI580050:GI23-584-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Balac_0584Imported
OrganismiBifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)Imported
Taxonomic identifieri580050 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000002343: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei66 – 661N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi580050.Balac_0584.

Structurei

3D structure databases

ProteinModelPortaliC6A761.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiYGHGLER.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6A761-1 [UniParc]FASTAAdd to Basket

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MVCMSVSALE EWQFSSEQGE RNYNQALREY PAQVIVDLAA LRDNMRHLVD    50
ITNREGGPTE VMGVVKADAY GHGLVPSALA ALAGGATWLG VAQAREALAL 100
RNAGIGVDRA RVLTWVNNPL HAPYDDLIAA DVDLSVATLT AIQKIAEAAR 150
AVGKPARVHI KVDTGFGRNG FTLAQIDSAI DLLLPLVDEG VFEIVGQWSH 200
LAVADAPAVG EFVEKTDEQI RVFEEFTSRL HARGIEPRIR HLANTAATLS 250
RPEIHYDLVR PGVALYGYEA DPAMGTPSKY ELRPAMTLQA QLSSVKNVGA 300
GEGLSYGRVY VTDEPTSAAI VPVGYADGIH RSASGFNEAG SKHVNKPGAP 350
VRVMTRDGAR IFHVSGRVCM DQFILDLHGD AENMGVHIGD TVELFGPGRG 400
EDYLEPTADD WARAADTISY EIFTCLRNRV PRLYANAFEV LDETDLGKLD 450
QSTLL 455
Length:455
Mass (Da):49,253
Last modified:September 1, 2009 - v1
Checksum:i7C040E0385AB7865
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001515 Genomic DNA. Translation: ACS45959.1.
RefSeqiYP_002968021.1. NC_012814.1.

Genome annotation databases

EnsemblBacteriaiACS45959; ACS45959; Balac_0584.
GeneIDi8008552.
KEGGiblc:Balac_0584.
PATRICi21107387. VBIBifAni84420_0593.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001515 Genomic DNA. Translation: ACS45959.1 .
RefSeqi YP_002968021.1. NC_012814.1.

3D structure databases

ProteinModelPortali C6A761.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 580050.Balac_0584.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACS45959 ; ACS45959 ; Balac_0584 .
GeneIDi 8008552.
KEGGi blc:Balac_0584.
PATRICi 21107387. VBIBifAni84420_0593.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi YGHGLER.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BANI580050:GI23-584-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bl-04 / DGCC2908 / RB 4825 / SD5219.

Entry informationi

Entry nameiC6A761_BIFLB
AccessioniPrimary (citable) accession number: C6A761
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: July 9, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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