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C6A761

- C6A761_BIFLB

UniProt

C6A761 - C6A761_BIFLB

Protein

Alanine racemase

Gene

Balac_0584

Organism
Bifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei66 – 661Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei168 – 1681SubstrateUniRule annotation
    Active sitei306 – 3061Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei370 – 3701Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBANI580050:GI23-584-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Balac_0584Imported
    OrganismiBifidobacterium animalis subsp. lactis (strain Bl-04 / DGCC2908 / RB 4825 / SD5219)Imported
    Taxonomic identifieri580050 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
    ProteomesiUP000002343: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei66 – 661N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi580050.Balac_0584.

    Structurei

    3D structure databases

    ProteinModelPortaliC6A761.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiYGHGLER.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6A761-1 [UniParc]FASTAAdd to Basket

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    MVCMSVSALE EWQFSSEQGE RNYNQALREY PAQVIVDLAA LRDNMRHLVD    50
    ITNREGGPTE VMGVVKADAY GHGLVPSALA ALAGGATWLG VAQAREALAL 100
    RNAGIGVDRA RVLTWVNNPL HAPYDDLIAA DVDLSVATLT AIQKIAEAAR 150
    AVGKPARVHI KVDTGFGRNG FTLAQIDSAI DLLLPLVDEG VFEIVGQWSH 200
    LAVADAPAVG EFVEKTDEQI RVFEEFTSRL HARGIEPRIR HLANTAATLS 250
    RPEIHYDLVR PGVALYGYEA DPAMGTPSKY ELRPAMTLQA QLSSVKNVGA 300
    GEGLSYGRVY VTDEPTSAAI VPVGYADGIH RSASGFNEAG SKHVNKPGAP 350
    VRVMTRDGAR IFHVSGRVCM DQFILDLHGD AENMGVHIGD TVELFGPGRG 400
    EDYLEPTADD WARAADTISY EIFTCLRNRV PRLYANAFEV LDETDLGKLD 450
    QSTLL 455
    Length:455
    Mass (Da):49,253
    Last modified:September 1, 2009 - v1
    Checksum:i7C040E0385AB7865
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001515 Genomic DNA. Translation: ACS45959.1.
    RefSeqiYP_002968021.1. NC_012814.1.

    Genome annotation databases

    EnsemblBacteriaiACS45959; ACS45959; Balac_0584.
    GeneIDi8008552.
    KEGGiblc:Balac_0584.
    PATRICi21107387. VBIBifAni84420_0593.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001515 Genomic DNA. Translation: ACS45959.1 .
    RefSeqi YP_002968021.1. NC_012814.1.

    3D structure databases

    ProteinModelPortali C6A761.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 580050.Balac_0584.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACS45959 ; ACS45959 ; Balac_0584 .
    GeneIDi 8008552.
    KEGGi blc:Balac_0584.
    PATRICi 21107387. VBIBifAni84420_0593.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi YGHGLER.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BANI580050:GI23-584-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bl-04 / DGCC2908 / RB 4825 / SD5219Imported.

    Entry informationi

    Entry nameiC6A761_BIFLB
    AccessioniPrimary (citable) accession number: C6A761
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3