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C6A4V3 (C6A4V3_THESM) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length196 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding16 – 238ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding94 – 974ATP By similarity HAMAP-Rule MF_00124

Sites

Active site951Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1511Zinc By similarity HAMAP-Rule MF_00124
Metal binding1541Zinc By similarity HAMAP-Rule MF_00124
Metal binding1891Zinc By similarity HAMAP-Rule MF_00124
Metal binding1921Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
C6A4V3 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 92C8F9910DAC96C2

FASTA19622,030
        10         20         30         40         50         60 
MVKFMHPEGF LEVITGPMFA GKTSELIKRI ERQIFAKRKA ALFKPSIDNR YSEDKLVAHN 

        70         80         90        100        110        120 
GLSYEAFVIP TTEEGVKMIY QKTKKEGFEV IGIDEVQFFP MSIVEILDKL ADEGIYVIAS 

       130        140        150        160        170        180 
GLNLDFKGDA FEVTKELLAM ADNIVYLTAI CSVCGREATR TQRLINGKPA PRDSPRILVG 

       190 
GMEAYEARCR KHHIVP 

« Hide

References

[1]"Metabolic versatility and indigenous origin of the archaeon Thermococcus sibiricus, isolated from a siberian oil reservoir, as revealed by genome analysis."
Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V., Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.
Appl. Environ. Microbiol. 75:4580-4588(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MM 739 / DSM 12597.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001463 Genomic DNA. Translation: ACS90648.1.
RefSeqYP_002994997.1. NC_012883.1.

3D structure databases

ProteinModelPortalC6A4V3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING604354.TSIB_1597.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS90648; ACS90648; TSIB_1597.
GeneID8096607.
KEGGtsi:TSIB_1597.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076390.
KOK00857.
OMADHISEST.

Enzyme and pathway databases

BioCycTSIB604354:GHMS-1640-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6A4V3_THESM
AccessionPrimary (citable) accession number: C6A4V3
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)