C6A4T6 (C6A4T6_THESM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402
Short name=BPG-independent PGAM HAMAP MF_01402
Short name=Phosphoglyceromutase HAMAP MF_01402
Short name=aPGAM HAMAP MF_01402
EC=5.4.2.1 HAMAP MF_01402

Gene names

Name:	apgM HAMAP MF_01402
Ordered Locus Names:	TSIB_1580

Organism

Thermococcus sibiricus (strain MM 739 / DSM 12597) [Complete proteome] [HAMAP]

Taxonomic identifier

604354 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily. HAMAP MF_01402

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01402
Molecular function	Isomerase HAMAP MF_01402 EMBL ACS90631.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6A4T6 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 3B83D4C9EC319CB8	FASTA	410	45,241
	10 20 30 40 50 60 MKRKGILIIL DGLGDRLIKE LGGKTPLEYA NTPNMDELAK MGILGQQDPI APGKPAGSDT 70 80 90 100 110 120 AHLAIFGYDP YQTYRGRGFF EALGVGLDLD EDDLAFRVNF ATIENGIITD RRAGRISTEE 130 140 150 160 170 180 AHELAKAIQE NVKLPVEFIF VGATGHRAVL VLKGMANGYK VGENDPHEAG KPPHKFEYAD 190 200 210 220 230 240 EESKKVAEIL EEFVKKAHEV LERHPINEKR RKEGKPVANY LLIRGAGTYP NIPMKFTEEW 250 260 270 280 290 300 KVKAAAVVAT ALVKGVARAI GFDVYTPEGA TGEYNTDPMA KAKKAVELLE EYDFVFLHFK 310 320 330 340 350 360 PTDAAGHDNN PMKKVEMIEK ADEMIGYIME NIDLEKTVIA ITGDHSTPCE VKNHSGDPVP 370 380 390 400 410 LLIVGGGVRT DDRETFSERE CMRGGIGRVR GKYIVPMIMD LMGRTEKFGA

References

[1]

"Metabolic versatility and indigenous origin of the archaeon Thermococcus sibiricus, isolated from a siberian oil reservoir, as revealed by genome analysis." Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V., Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G. Appl. Environ. Microbiol. 75:4580-4588(2009) [PubMed: 19447963] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001463 Genomic DNA. Translation: ACS90631.1.
RefSeq	YP_002994980.1. NC_012883.1.
3D structure databases
ProteinModelPortal	C6A4T6.
ModBase	Search...
Protein-protein interaction databases
STRING	C6A4T6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8096589.
GenomeReviews	Gene locus TSIB_1580 in contig CP001463_GR.
KEGG	tsi:TSIB_1580.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6A4T6_THESM

Accession

Primary (citable) accession number: C6A4T6

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)