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Protein

Ribonuclease P protein component 2

Gene

rnp2

Organism
Thermococcus sibiricus (strain MM 739 / DSM 12597)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
Biological processtRNA processing

Enzyme and pathway databases

BioCyciTSIB604354:G1GV3-1324-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 2UniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P component 2UniRule annotation
Alternative name(s):
Pop5UniRule annotation
Gene namesi
Name:rnp2UniRule annotation
Ordered Locus Names:TSIB_1353
OrganismiThermococcus sibiricus (strain MM 739 / DSM 12597)
Taxonomic identifieri604354 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000009079 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002128601 – 120Ribonuclease P protein component 2Add BLAST120

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

Protein-protein interaction databases

STRINGi604354.TSIB_1353

Structurei

3D structure databases

SMRiC6A460
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic/archaeal RNase P protein component 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01365 Archaea
COG1369 LUCA
HOGENOMiHOG000286243
KOiK03537
OMAiNPWLIDY
OrthoDBiPOG093Z0EPO

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
HAMAPiMF_00755 RNase_P_2, 1 hit
InterProiView protein in InterPro
IPR002759 RNase_P/MRP_subunit
IPR016434 RNase_P_comp-2
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
PIRSFiPIRSF004952 RNase_P_2, 1 hit

Sequencei

Sequence statusi: Complete.

C6A460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRKPKTLPP TLRDKNRYIA FQVTGERPFK KEMIKKAIWD VSLKTLGELG
60 70 80 90 100
TARAKPWFIK FDEKTQTGIV RCDRKYVEEI RFVLTLITEI NGSKAIVRTL
110 120
GVSGTIKRLK MKFLKEFGWK
Length:120
Mass (Da):14,061
Last modified:September 1, 2009 - v1
Checksum:iA1CEDD4EF0716D9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001463 Genomic DNA Translation: ACS90405.1
RefSeqiWP_015849623.1, NC_012883.1

Genome annotation databases

EnsemblBacteriaiACS90405; ACS90405; TSIB_1353
GeneIDi8096354
KEGGitsi:TSIB_1353

Similar proteinsi

Entry informationi

Entry nameiRNP2_THESM
AccessioniPrimary (citable) accession number: C6A460
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 1, 2009
Last modified: March 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health