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C6A2T7 (C6A2T7_THESM) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904

Short name=PEPC HAMAP-Rule MF_01904
Short name=PEPCase HAMAP-Rule MF_01904
EC=4.1.1.31 HAMAP-Rule MF_01904
Gene names
Name:ppcA HAMAP-Rule MF_01904
Ordered Locus Names:TSIB_0872 EMBL ACS89932.1
OrganismThermococcus sibiricus (strain MM 739 / DSM 12597) [Complete proteome] [HAMAP] EMBL ACS89932.1
Taxonomic identifier604354 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family. HAMAP-Rule MF_01904

Sequences

Sequence LengthMass (Da)Tools
C6A2T7 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: FA5093DA6098E8AF

FASTA48556,423
        10         20         30         40         50         60 
MIFVSLVDYM IPRTMSTQHP DNVYIPFFAH ESSLGGEDEV LEAFYAFSVL GVQEQMWDFE 

        70         80         90        100        110        120 
GKEVDEFVIK KLLEKYGQFF KKKKLGRDIR ITPRVPNPSV EKAEAKLLLE TLESIPRSAD 

       130        140        150        160        170        180 
YAKLFYGEEI APIFEVILPM TTSSKEIERV YELYKRYIIG KQYKRVYDIK IYEWIGEFYP 

       190        200        210        220        230        240 
EEINVIPLFE TKEAILNSHE ILKEYLTGKN FEYQRVFLAR SDPAMNYGLI SAVIYDKYAL 

       250        260        270        280        290        300 
FNIQELEEEL SVPIYPIIGV GSAPFRGHFI PENVENTIKE YPNVQTFTVQ SSFKYDNDPK 

       310        320        330        340        350        360 
EVIRAIEKVN ERKRKKSASV DEGVFKILEK YEKEYTAELK LLAPYIREIA KFVPSRRKRK 

       370        380        390        400        410        420 
LHIGLFGYSR KINGEVLPRA IKFTASLYSL GVPPELLGLS TLSEKDIEEL AEYYYGLYRD 

       430        440        450        460        470        480 
LEFALKFFNP KTSQKFKFLN KIVKLQKEMG IEAEERHQTL TSQIISGKFE ESVIVQAADI 


RGFLG 

« Hide

References

[1]"Metabolic versatility and indigenous origin of the archaeon Thermococcus sibiricus, isolated from a siberian oil reservoir, as revealed by genome analysis."
Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V., Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G.
Appl. Environ. Microbiol. 75:4580-4588(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MM 739 / DSM 12597.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001463 Genomic DNA. Translation: ACS89932.1.
RefSeqYP_002994281.1. NC_012883.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING604354.TSIB_0872.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS89932; ACS89932; TSIB_0872.
GeneID8095863.
KEGGtsi:TSIB_0872.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHOG000038601.
KOK01595.
OMAPRAIKFT.
ProtClustDBPRK13655.

Enzyme and pathway databases

BioCycTSIB604354:GHMS-896-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6A2T7_THESM
AccessionPrimary (citable) accession number: C6A2T7
Entry history
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 19, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)