C6A2T7 (C6A2T7_THESM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
Short name=PEPC HAMAP-Rule MF_01904
Short name=PEPCase HAMAP-Rule MF_01904
EC=4.1.1.31 HAMAP-Rule MF_01904

Gene names

Name:	ppcA HAMAP-Rule MF_01904
Ordered Locus Names:	TSIB_0872 EMBL ACS89932.1

Organism

Thermococcus sibiricus (strain MM 739 / DSM 12597) [Complete proteome] [HAMAP] EMBL ACS89932.1

Taxonomic identifier

604354 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus › Thermococcus sibiricus

Protein attributes

Sequence length	485 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904
Cofactor	Magnesium By similarity. HAMAP-Rule MF_01904
Subunit structure	Homotetramer By similarity. HAMAP-Rule MF_01904
Sequence similarities	Belongs to the PEPCase type 2 family. HAMAP-Rule MF_01904

Ontologies

Keywords
Biological process	Carbon dioxide fixation HAMAP-Rule MF_01904
Ligand	Magnesium HAMAP-Rule MF_01904 Pyruvate EMBL ACS89932.1
Molecular function	Lyase HAMAP-Rule MF_01904 EMBL ACS89932.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6A2T7 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: FA5093DA6098E8AF	FASTA	485	56,423
	10 20 30 40 50 60 MIFVSLVDYM IPRTMSTQHP DNVYIPFFAH ESSLGGEDEV LEAFYAFSVL GVQEQMWDFE 70 80 90 100 110 120 GKEVDEFVIK KLLEKYGQFF KKKKLGRDIR ITPRVPNPSV EKAEAKLLLE TLESIPRSAD 130 140 150 160 170 180 YAKLFYGEEI APIFEVILPM TTSSKEIERV YELYKRYIIG KQYKRVYDIK IYEWIGEFYP 190 200 210 220 230 240 EEINVIPLFE TKEAILNSHE ILKEYLTGKN FEYQRVFLAR SDPAMNYGLI SAVIYDKYAL 250 260 270 280 290 300 FNIQELEEEL SVPIYPIIGV GSAPFRGHFI PENVENTIKE YPNVQTFTVQ SSFKYDNDPK 310 320 330 340 350 360 EVIRAIEKVN ERKRKKSASV DEGVFKILEK YEKEYTAELK LLAPYIREIA KFVPSRRKRK 370 380 390 400 410 420 LHIGLFGYSR KINGEVLPRA IKFTASLYSL GVPPELLGLS TLSEKDIEEL AEYYYGLYRD 430 440 450 460 470 480 LEFALKFFNP KTSQKFKFLN KIVKLQKEMG IEAEERHQTL TSQIISGKFE ESVIVQAADI RGFLG

References

[1]

"Metabolic versatility and indigenous origin of the archaeon Thermococcus sibiricus, isolated from a siberian oil reservoir, as revealed by genome analysis." Mardanov A.V., Ravin N.V., Svetlitchnyi V.A., Beletsky A.V., Miroshnichenko M.L., Bonch-Osmolovskaya E.A., Skryabin K.G. Appl. Environ. Microbiol. 75:4580-4588(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MM 739 / DSM 12597.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001463 Genomic DNA. Translation: ACS89932.1.
RefSeq	YP_002994281.1. NC_012883.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	604354.TSIB_0872.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS89932; ACS89932; TSIB_0872.
GeneID	8095863.
KEGG	tsi:TSIB_0872.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1892.
HOGENOM	HOG000038601.
KO	K01595.
OMA	MCTQHPD.
ProtClustDB	PRK13655.
Family and domain databases
HAMAP	MF_01904. PEPcase_type2.
InterPro	IPR007566. PEP_COase_arc-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
PIRSF	PIRSF006677. UCP006677. 1 hit.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMs	TIGR02751. PEPCase_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6A2T7_THESM

Accession

Primary (citable) accession number: C6A2T7

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)