ID   C5Z041_SORBI            Unreviewed;       744 AA.
AC   C5Z041;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 72.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=SORBI_3009G044800 {ECO:0000313|EMBL:EES19028.1};
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558 {ECO:0000313|EMBL:EES19028.1, ECO:0000313|Proteomes:UP000000768};
RN   [1] {ECO:0000313|EMBL:EES19028.1, ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=19189423; DOI=10.1038/nature07723;
RA   Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA   Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA   Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA   Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA   Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA   Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA   Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA   Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT   "The Sorghum bicolor genome and the diversification of grasses.";
RL   Nature 457:551-556(2009).
RN   [2] {ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=29161754; DOI=10.1111/tpj.13781;
RA   McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA   Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA   Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT   "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT   a transcriptome atlas, and signatures of genome organization.";
RL   Plant J. 93:338-354(2018).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; CM000768; EES19028.1; -; Genomic_DNA.
DR   RefSeq; XP_002440598.1; XM_002440553.1.
DR   AlphaFoldDB; C5Z041; -.
DR   STRING; 4558.C5Z041; -.
DR   EnsemblPlants; EES19028; EES19028; SORBI_3009G044800.
DR   GeneID; 8075980; -.
DR   Gramene; EES19028; EES19028; SORBI_3009G044800.
DR   KEGG; sbi:8075980; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   HOGENOM; CLU_004747_3_0_1; -.
DR   InParanoid; C5Z041; -.
DR   OMA; DSFKERM; -.
DR   OrthoDB; 21270at2759; -.
DR   Proteomes; UP000000768; Chromosome 9.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF143; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          389..619
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   744 AA;  86831 MW;  3CC378E58BE93330 CRC64;
     MAGQERRTID LEEGWAFMQK GITKLKNILE GKPEPQFSSE DYMMLYTTIY NMCTQKPPHD
     YSQQLYDKYR ESFEEYITSM VLPSLREKHD EFMLRELVQR WSNHKVMVRW LSRFFHYLDR
     YFISRRSLTP LKEVGLTCFR ELIYQEIKGQ VKDAVIALID KEREGEQIDR ALLKNVLDIF
     VEIGLGQMEC YENDFEDFLL KDTTEYYSVK AQSWILEDSC PDYMIKAEEC LKREKERVGH
     YLHISSEQKL LEKVQNELLA QYATPLLEKE HSGCSALLRD DKVEDLSRMY RLFSKITRGL
     EPISNMFKTH VTNEGTALVK QAEDSASNKK PEKKDMVGMQ EQVFVWKIIE LHDKYVAYVT
     ECFQGHTLFH KALKEAFEVF CNKGVSGSSS AELLATFCDN ILKKGCSEKL SDEAIEDALE
     KVVRLLAYIS DKDLFAEFYR KKLARRLLFD KSANDEHERS ILTKLKQQCG GQFTSKMEGM
     VTDLTVARDH QTKFEEFVAG HPELNPGIDL AVTVLTTGFW PSYKTFDINL PAEMVKCVEV
     FKEFYQTRTK HRKLTWIYSL GTCNINAKFD AKPIELIVTT YQAALLLLFN GSDRLSYSEI
     VTQLNLSDDD VVRLLHSLSC AKYKILTKEP ANRSISPNDV FEFNSKFTDR MRRIKIPLPP
     VDEKKKVVED VDKDRRYAID ASIVRIMKSR KVMGHQQLVA ECVEQLSRMF KPDFKAIKKR
     IEDLITRDYL ERDKDNANMY KYLA
//